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H U Weltzien

Explore the profile of H U Weltzien including associated specialties, affiliations and a list of published articles. Areas
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Articles 71
Citations 769
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Recent Articles
1.
Preckel T, Hellwig S, Pflugfelder U, Lappin M, Weltzien H
Immunology . 2001 Feb; 102(1):8-14. PMID: 11168631
Clonal T-cell anergy has been proposed as a mechanism to ensure peripheral tolerance in vivo. Anergy has been reported to result from T cell activation with inappropriate antigen-presenting cells (APC)...
2.
Vollmer J, Weltzien H, Gamerdinger K, Lang S, Choleva Y, Moulon C
Int Immunol . 2000 Dec; 12(12):1723-31. PMID: 11099312
VB17(+) TCR dominate in Ni-driven T cell cultures from highly Ni-sensitized patients. Using transfection of TCR from three CD4(+), VB17(+), Ni-specific human T cell clones, we studied their Ni-MHC contacts...
3.
Maier R, Moulon C, Weltzien H, Meyerhans A
Blood . 2000 Aug; 96(5):1853-6. PMID: 10961886
The chemokine receptors CCR5 and CXCR4 are coreceptors for the human immunodeficiency virus (HIV) and determine the cell tropism of different HIV strains. Previous studies on their regulation were performed...
4.
Martin S, Lappin M, Kohler J, Delattre V, Leicht C, Preckel T, et al.
J Invest Dermatol . 2000 Aug; 115(2):260-6. PMID: 10951244
The identity of the effector T cell population involved in contact hypersensitivity is still questionable with evidence promoting both CD4+ or CD8+ T cells. Previous experimental studies have relied on...
5.
Vollmer J, Weltzien H, Dormoy A, Pistoor F, Moulon C
J Invest Dermatol . 1999 Sep; 113(2):175-81. PMID: 10469300
Nickel-induced contact dermatitis represents a T cell mediated delayed type hyperreactivity. The elucidation of the molecular basis of T cell activation by Ni2+ ions may serve as a model for...
6.
Vollmer J, Weltzien H, Moulon C
J Immunol . 1999 Aug; 163(5):2723-31. PMID: 10453014
Nickel is the most common inducer of contact sensitivity in humans. We previously found that overrepresentation of the TCRBV17 element in Ni-induced CD4+ T cell lines of Ni-allergic patients relates...
7.
Padovan E, von Greyerz S, Pichler W, Weltzien H
J Immunol . 1999 Jan; 162(2):1171-7. PMID: 9916749
The activation of CD4+ T lymphocytes upon Ag stimulation plays a critical role in adverse immune responses including drug-specific hypersensitivity reactions. We examined the modulation of T cell phenotype induced...
8.
Preckel T, Breloer M, Kohler H, von Bonin A, Weltzien H
Eur J Immunol . 1998 Dec; 28(11):3706-18. PMID: 9842913
We recently demonstrated antagonism for hapten-reactive T cells by altered hapten ligands. Here we investigated partial peptide- or hapten-agonism and effects of antigen stimulation on the expression of TCR and...
9.
Moulon C, Wild D, Dormoy A, Weltzien H
J Invest Dermatol . 1998 Sep; 111(3):360-6. PMID: 9740224
T lymphocytes are critical effectors in the pathogenesis of contact hypersensitivity. Nickel is the most common contact sensitizer in humans and nickel-specific CD4+ T helper cells have been extensively characterized....
10.
Denfeld R, Tesmann J, Dittmar H, Weiss J, Schopf E, Weltzien H, et al.
Photochem Photobiol . 1998 Jun; 67(5):554-60. PMID: 9613238
We have reported previously that low-dose UVB radiation (UVBR, 50-200 J/m2) perturbs the antigen-presenting cell (APC) function of murine Langerhans cells (LC) by interfering with yet undefined costimulatory signals. In...