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H U Holst

Explore the profile of H U Holst including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 5
Citations 98
Followers 0
Related Specialties
Biochemistry
Genetics
Microbiology
Top 10 Co-Authors
L Bolund
N Gregersen
T J Corydon
S Kolvraa
P H Andreasen
P Bross
M M Jorgensen
G Christiansen
M L Larsen
L G Jensen
Published In
Mol Microbiol
J Biol Chem
Biochem J
Eur J Hum Genet
Clin Genet
Affiliations
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Recent Articles
1.
LDL receptor-GFP fusion proteins: new tools for the characterisation of disease-causing mutations in the LDL receptor gene
Holst H, Dagnaes-Hansen F, Corydon T, Andreasen P, Jorgensen M, Kolvraa S, et al.
Eur J Hum Genet . 2002 Jan; 9(11):815-22. PMID: 11781697
The function of a series of LDL receptor GFP fusion proteins with different, flexible, unstructured spacer regions was analysed. An optimised version of the fusion protein was used to analyse...
2.
Grp78 is involved in retention of mutant low density lipoprotein receptor protein in the endoplasmic reticulum
Jorgensen M, Jensen O, Holst H, Hansen J, Corydon T, Bross P, et al.
J Biol Chem . 2000 Jul; 275(43):33861-8. PMID: 10906332
The low density lipoprotein (LDL) receptor is responsible for removing the majority of the LDL cholesterol from the plasma. Mutations in the LDL receptor gene cause the disease familial hypercholesterolemia...
3.
Normolipidemia and hypercholesterolemia in persons heterozygous for the same 1592 + 5G --> A splice site mutation in the low-density lipoprotein receptor gene
Jensen H, Jensen L, Holst H, Andreasen P, Hansen P, Larsen M, et al.
Clin Genet . 2000 Feb; 56(5):378-88. PMID: 10668928
In the present study, we have characterized a unique splice donor G to A substitution in the moderately conserved + 5 position in intron 10 of the low-density lipoprotein (LDL)...
4.
A human homologue of Escherichia coli ClpP caseinolytic protease: recombinant expression, intracellular processing and subcellular localization
Corydon T, Bross P, Holst H, Neve S, Kristiansen K, Gregersen N, et al.
Biochem J . 1998 May; 331 ( Pt 1):309-16. PMID: 9512494
We have recently cloned a human cDNA (hClpP) with significant sequence similarity to the ATP-dependent Escherichia coli ClpP protease [Bross, Andresen, Knudsen, Kruse and Gregersen (1995) FEBS Lett. 377, 249-252]....
5.
Chlamydia trachomatis utilizes the host cell microtubule network during early events of infection
Clausen J, Christiansen G, Holst H, Birkelund S
Mol Microbiol . 1997 Aug; 25(3):441-9. PMID: 9302007
The host cell cytoskeleton is known to play a vital role in the life cycles of several pathogenic intracellular microorganisms by providing the basis for a successful invasion and by...