H S Feldman
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Explore the profile of H S Feldman including associated specialties, affiliations and a list of published articles.
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58
Citations
234
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Recent Articles
1.
Bass A, Darpo B, Breidenbach A, Bruse K, Feldman H, Garnes D, et al.
Br J Pharmacol
. 2008 Jul;
154(7):1491-501.
PMID: 18663380
Knowledge of the cardiac safety of emerging new drugs is an important aspect of assuring the expeditious advancement of the best candidates targeted at unmet medical needs while also assuring...
2.
Feldman H, DVOSKIN S, Halldin M, Ask A, Doucette A
Reg Anesth
. 1997 Oct;
22(5):451-60.
PMID: 9338908
Background And Objectives: Ropivacaine is the S(-) propyl homolog of bupivacaine and mepivacaine. Studies in humans have confirmed the results of studies in laboratory animals that ropivacaine is a long-acting...
3.
Vladimirov M, Thalhammer J, Hunt N, Feldman H, Strichartz G
Anesthesiology
. 1997 Apr;
86(4):945-56.
PMID: 9105239
Background: The quest for a drug that would provide analgesia with minimal motor deficiency, through the selective inhibition of impulses in small-diameter fibers, was brightened by a previous report of...
4.
Feldman H, Hartvig P, Wiklund L, Doucette A, Antoni G, Gee A, et al.
Biopharm Drug Dispos
. 1997 Mar;
18(2):151-64.
PMID: 9099451
The regional myocardial uptake and kinetics of 11C-lidocaine, 11C-bupivacaine, and 11C-ropivacaine were examined in the pig, utilizing positron emission tomography to determine whether disproportionate distribution exists among these agents. The...
5.
Feldman H, DVOSKIN S, Arthur G, Doucette A
Reg Anesth
. 1996 Jul;
21(4):318-26.
PMID: 8837190
Background And Objectives: This study was initiated to evaluate the antinociceptive and motor blocking capabilities of epidurally administered 0.5% and 0.75% ropivacaine and bupivacaine using a blinded, random crossover design...
6.
Pitkanen M, Feldman H, Arthur G, COVINO B
Reg Anesth
. 1992 Jul;
17(4):183-92.
PMID: 1515382
Background And Objectives: The purpose of this study was to compare the inotropic and chronotropic effects of ropivacaine, bupivacaine, and lidocaine in an isolated, spontaneously beating rabbit heart preparation. The...
7.
Hurley R, Feldman H, Latka C, Arthur G, COVINO B
Reg Anesth
. 1991 Nov;
16(6):303-8.
PMID: 1772811
Ropivacaine is a new local anesthetic that is chemically related to mepivacaine and bupivacaine. Previous laboratory studies have demonstrated that ropivacaine possesses an anesthetic profile similar to that of bupivacaine...
8.
Feldman H, Arthur G, Pitkanen M, Hurley R, Doucette A, COVINO B
Anesth Analg
. 1991 Oct;
73(4):373-84.
PMID: 1897763
Two groups of six beagle dogs received rapid intravenous (IV) injections of ropivacaine or bupivacaine on two occasions in a blinded random fashion. Initially, a dose sufficient to cause convulsions...
9.
Heard S, Baum T, Feldman H, Latka C, Fink M
Crit Care Med
. 1991 May;
19(5):723-7.
PMID: 1902766
Background And Methods: We tested the hypothesis that a sublethal dose of lipopolysaccharide in vivo induces in vitro atrial depression in rats via release of cyclooxygenase products. Male Sprague-Dawley rats...
10.
Baum T, Heard S, Feldman H, Latka C, Fink M
J Surg Res
. 1990 Jun;
48(6):629-34.
PMID: 2194072
We tested the hypothesis that lipopolysaccharide (LPS)-induced myocardial dysfunction is mediated by cyclooxygenase-derived metabolites of arachidonic acid or platelet activating factor (PAF). Ether-anesthetized rats were injected iv with normal saline...