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H Paul Ehrlich

Explore the profile of H Paul Ehrlich including associated specialties, affiliations and a list of published articles. Areas
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Articles 54
Citations 1106
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Recent Articles
1.
Hazard 3rd S, Zwemer C, Mackay D, Koduru S, Ravnic D, Ehrlich H
J Surg Res . 2016 Dec; 207:102-107. PMID: 27979464
Background: There are over two million laparotomies performed in the United States each year with an incisional hernia rate between 2% and 11%. A total of 100,000 ventral hernia repairs...
2.
Dallon J, Evans E, Ehrlich H
J R Soc Interface . 2014 Aug; 11(99). PMID: 25142520
Two mathematical models for fibroblast-collagen interaction are proposed which reproduce qualitative features of fibroblast-populated collagen lattice contraction. Both models are force based and model the cells as individual entities with...
3.
Foley T, Ehrlich H
Plast Reconstr Surg . 2014 Apr; 133(5):638e-644e. PMID: 24776565
Background: Dexamethasone, a common therapy for reducing hypertrophic scar, sometimes fails. However, in cell culture, all dexamethasone-treated fibroblasts die. In co-cultures, gap junction intercellular communications between mast cells and fibroblasts...
4.
Ehrlich H
Adv Wound Care (New Rochelle) . 2014 Feb; 2(4):113-121. PMID: 24527335
Significance: The repair of wounds usually terminates with a scar. The healing from a severe tissue loss can create a new clinical problem, excessive scarring. Approaches to prevent excessive scarring...
5.
Ehrlich H, Hunt T
Adv Wound Care (New Rochelle) . 2014 Feb; 1(1):3-9. PMID: 24527271
Background: Open wound closure by wound contraction produces a healed defect made up mostly of dermis. Generating thicker collagen fibers condenses granulation tissue, which pulls surrounding skin into the defect....
6.
Ehrlich H, Moyer K
Methods Mol Biol . 2013 Sep; 1037:45-58. PMID: 24029929
The fibroblast-populated collagen lattice (FPCL) was intended to act as the dermal component for "skin-equivalent" or artificial skin developed for skin grafting burn patients. The "skin-equivalent" was clinically unsuccessful as...
7.
Foley T, Ehrlich H
Plast Reconstr Surg . 2013 May; 131(5):1036-1044. PMID: 23629085
Background: The prominent inflammatory cell identified in excessive scarring is the mast cell. Hypertrophic scar exhibits myofibroblasts derived from the transformation of fibroblasts, increased collagen synthesis, and stationary nonmigratory resident...
8.
Moyer K, Ehrlich H
Plast Reconstr Surg . 2013 Apr; 131(4):680-685. PMID: 23542241
Background: Breast implant capsular contracture is a common complication of implant-based breast reconstruction. To develop nonsurgical interventions to combat breast capsular contractures, a clearer understanding of the process is required....
9.
Ehrlich H, Hazard S
Ann N Y Acad Sci . 2012 Oct; 1269:74-8. PMID: 23045973
In previous studies, granulation tissue from subcutaneous sponge implants in rats receiving thymosin β4, a 43-amino acid actin-binding protein that advances wound repair, produced the unexpected absence of myofibroblast populations,...
10.
Gunn J, Ehrlich H
Plast Reconstr Surg . 2012 Jan; 129(2):300e-306e. PMID: 22286444
Background: Severed tendon repair advances with either a scar through extrinsic repair or regeneration through intrinsic repair. The authors examined whether intrinsic tendon repair reintroduces embryonic fibrillogenesis, whereby preformed collagen...