H P Vollmers
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Explore the profile of H P Vollmers including associated specialties, affiliations and a list of published articles.
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40
Citations
388
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Recent Articles
1.
Vollmers H, Brandlein S
Histol Histopathol
. 2006 Sep;
21(12):1355-66.
PMID: 16977586
Over the years, natural IgM antibodies were considered as the parias among the immune competent molecules. Their characteristic properties, like low affinity, cross-reactivity and pentameric structure, were assessed as difficult...
2.
Vollmers H, Brandlein S
Histol Histopathol
. 2005 Jun;
20(3):927-37.
PMID: 15944943
Precancerous epithelial lesions are sites of uncontrolled cellular proliferation generated by irreversible genetic alterations. Not all of those lesions progress to invasive cancer, some may even regress, but the early...
3.
Vollmers H, Brandlein S
Methods Find Exp Clin Pharmacol
. 2005 Apr;
27(3):185-91.
PMID: 15834451
Stress kills and hence should be avoided. On the other hand, stress induction can be used to remove malignant cells by inducing cellular suicide. Natural IgM antibodies act as first-line...
4.
Brandlein S, Vollmers H
Histol Histopathol
. 2004 May;
19(3):897-905.
PMID: 15168352
During its lifetime each multi-cellular organism is permanently exposed to infectious agents and transformed cells. Without an early recognition and a rapid elimination system, there would be no development and...
5.
Brandlein S, Pohle T, Vollmers C, Wozniak E, Ruoff N, Muller-Hermelink H, et al.
Oncol Rep
. 2004 Mar;
11(4):777-84.
PMID: 15010872
The human monoclonal antibody PAM-1 was isolated from a patient with stomach cancer. The germ-line coded IgM antibody identifies a recently described 130 kDa variant of CFR-1 (cysteine-rich fibroblast growth...
6.
Timmermann W, Illert B, Vollmers H, Krenn V, Ruckle-Lanz H, Wilhelm M, et al.
Kongressbd Dtsch Ges Chir Kongr
. 2003 Apr;
119:396-7.
PMID: 12704896
The antibody SC-1 is a human IGM molecule, which binds to a tumor specific receptor. This SC-1 receptor is detectable on biopsies, it is present in about 50% of gastric...
7.
Hensel F, Hermann R, Brandlein S, Krenn V, Schmausser B, Geis S, et al.
Lab Invest
. 2001 Nov;
81(11):1553-63.
PMID: 11706063
The human monoclonal antibody SC-1 was isolated from a patient with a diffuse-type adenocarcinoma of the stomach using somatic cell hybridization. The immunoglobulin (Ig)M antibody reacts specifically with diffuse- (70%)...
8.
Hermann R, Hensel F, Muller E, Keppler M, Souto-Carneiro M, Brandlein S, et al.
Hum Antibodies
. 2001 Oct;
10(2):83-90.
PMID: 11673663
Phosphorylation and activation of caspases play an important role in the induction of apoptosis. During tumor specific apoptosis, induced by the human monoclonal antibody SC-1, tyrosine phosphorylation and serine dephosphorylation...
9.
Hensel F, Brandlein S, Eck M, Schmidt K, Krenn V, Kloetzer A, et al.
Lab Invest
. 2001 Aug;
81(8):1097-108.
PMID: 11502861
The germline coded human monoclonal IgM antibody 103/51 was isolated from a gastric carcinoma patient. This antibody binds to a 130-kd membrane molecule and has a mitotic effect on tumor...
10.
Vollmers H, Timmermann W, Hensel F, Illert B, Thiede A, Muller-Hermelink H
Zentralbl Chir
. 2000 Aug;
125 Suppl 1:37-40.
PMID: 10929645
The human monoclonal antibody SC-1 was isolated from a patient with a diffuse-type adenocarcinoma of the stomach and induces apoptosis of stomach carcinoma cells by binding a stomach-carcinoma-associated isoform of...