H MUIRHEAD
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Explore the profile of H MUIRHEAD including associated specialties, affiliations and a list of published articles.
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Recent Articles
1.
Read J, Pearce J, Li X, MUIRHEAD H, Chirgwin J, Davies C
J Mol Biol
. 2001 May;
309(2):447-63.
PMID: 11371164
Phosphoglucose isomerase (PGI) is a multifunctional protein, which, inside the cell, functions as a housekeeping enzyme of glycolysis and gluconeogenesis and, outside the cell, exerts wholly unrelated cytokine properties. We...
2.
Kugler W, Willaschek C, Holtz C, Ohlenbusch A, Laspe P, Krugener R, et al.
Hum Mutat
. 2000 Feb;
15(3):261-72.
PMID: 10679942
Pyruvate kinase (PK) deficiency (PKD) is an autosomal recessive disorder with the typical manifestation of nonspherocytic hemolytic anemia. We analyzed the mutant enzymes of 10 unrelated patients with PKD, whose...
3.
Kugler W, Breme K, Laspe P, MUIRHEAD H, Davies C, Winkler H, et al.
Hum Genet
. 1998 Dec;
103(4):450-4.
PMID: 9856489
Glucose-6-phosphate isomerase (GPI) deficiency, an autosomal recessive genetic disorder with the typical manifestation of nonspherocytic haemolytic anaemia, can be associated in some cases with neurological impairment. GPI has been found...
4.
Ernest I, Callens M, Uttaro A, Chevalier N, Opperdoes F, MUIRHEAD H, et al.
Protein Expr Purif
. 1998 Aug;
13(3):373-82.
PMID: 9693062
A procedure was developed for overexpression of Trypanosoma brucei pyruvate kinase in Escherichia coli. The enzyme was purified to near-homogeneity from the bacterial lysate by first removing nucleic acids and...
5.
Lovell S, Mullick A, MUIRHEAD H
J Mol Biol
. 1998 May;
276(4):839-51.
PMID: 9500921
The enzyme pyruvate kinase (PK) from the moderate thermophile Bacillus stearothermophilus has been used as a model system with which to investigate the homotropic and heterotropic cooperative interactions of the...
6.
Chandra N, MUIRHEAD H, HOLBROOK J, Bernstein B, Hol W, Sessions R
Proteins
. 1998 Apr;
30(4):372-80.
PMID: 9533621
The occurrence of large domain motions associated with the mechanism of action of many proteins is well established. We present a general method of predicting domain closure applicable to proteins...
7.
Rawas A, MUIRHEAD H, Williams J
Acta Crystallogr D Biol Crystallogr
. 1997 Jul;
53(Pt 4):464-8.
PMID: 15299915
The structure of apo duck ovotransferrin (APODOT) has been determined at a resolution of 4.0 A by the molecular replacement method using the structure of duck ovotransferrin (DOT) as the...
8.
Davies C, Beauchamp J, Emery D, Rawas A, MUIRHEAD H
Acta Crystallogr D Biol Crystallogr
. 1997 Mar;
53(Pt 2):186-94.
PMID: 15299953
The structure of a Fab fragment of a monoclonal antibody (1583) that neutralizes a broad range of HIV-1 isolates has been solved by X-ray crystallography. This antibody is directed against...
9.
Collins R, Kelly S, Price N, Fothergill-Gilmore L, MUIRHEAD H
Protein Eng
. 1996 Dec;
9(12):1203-10.
PMID: 9010934
A mutant form of pyruvate kinase in which serine 384 has been mutated to proline has been engineered in the yeast Saccharomyces cerevisiae. Residue 384 is located in a helix...
10.
Rawas A, MUIRHEAD H, Williams J
Acta Crystallogr D Biol Crystallogr
. 1996 Jul;
52(Pt 4):631-40.
PMID: 15299626
The structure of diferric duck ovotransferrin (DOT) has been determined and refined at a resolution of 2.35 A. The DOT structure, which contains two iron binding sites, is similar to...