H Muhl
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Explore the profile of H Muhl including associated specialties, affiliations and a list of published articles.
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Articles
43
Citations
567
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Recent Articles
1.
Muhl H, Pfeilschifter J
Z Rheumatol
. 2011 Jan;
70(2):101-7.
PMID: 21267731
Since its introduction as a disease-modifying drug, methotrexate (MTX), a folate antagonist, is regarded as a major pillar of anti-rheumatic pharmacotherapy. This has not been changed in the current era...
2.
Ziesche E, Scheiermann P, Bachmann M, Sadik C, Hofstetter C, Zwissler B, et al.
Clin Exp Immunol
. 2009 Aug;
157(3):370-6.
PMID: 19664145
Interleukin (IL)-22 production triggered by innate immune mechanisms has been identified as key to efficient intestinal anti-bacterial host defence and preservation of homeostasis. We hypothesized that glucocorticoid therapy may impair...
3.
Gauer S, Sichler O, Obermuller N, Holzmann Y, Kiss E, Sobkowiak E, et al.
Kidney Int
. 2007 Aug;
72(9):1081-7.
PMID: 17687255
We determined the cellular location of interleukin-18 (IL-18) and caspase-1 and the purinergic receptor P2X7, two proteins necessary for its activation and secretion. The mRNA and protein of IL-18 were...
4.
Boost K, Flondor M, Hofstetter C, Platacis I, Stegewerth K, Hoegl S, et al.
Acta Anaesthesiol Scand
. 2007 Jul;
51(7):900-8.
PMID: 17635398
Background: Recent studies suggest that volatile anaesthetics have anti-inflammatory and preconditioning properties and that beta-adrenoceptors are involved in the signalling pathways for these effects. Concurrently, the blockade of beta-adrenoceptors has...
5.
Hofstetter C, Boost K, Flondor M, Basagan-Mogol E, Betz C, Homann M, et al.
Acta Anaesthesiol Scand
. 2007 Jul;
51(7):893-9.
PMID: 17635397
Background: Volatile anesthetics and hypothermia attenuate the inflammatory response. We aimed to compare the anti-inflammatory effects of sevoflurane and mild hypothermia during experimental endotoxemia in the rat. Methods: Anesthetized, ventilated...
6.
Moller B, Paulukat J, Nold M, Behrens M, Kukoc-Zivojnov N, Kaltwasser J, et al.
Rheumatology (Oxford)
. 2003 Mar;
42(3):442-5.
PMID: 12626794
Objective: To investigate expression of the endogenous antagonist of interleukin 18 (IL-18) bioactivity, IL-18 binding protein isoform a (IL-18BPa), in fibroblast-like synoviocytes (FLS). Methods: Long-term cultured FLS from rheumatoid arthritis...
7.
Paulukat J, Bosmann M, Nold M, Garkisch S, Kampfer H, Frank S, et al.
J Immunol
. 2001 Dec;
167(12):7038-43.
PMID: 11739524
IL-18 and IL-18 binding protein (IL-18BP) are two newly described opponents in the cytokine network. Local concentrations of these two players may determine biological functions of IL-18 in the context...
8.
Kampfer H, Paulukat J, Muhl H, Wetzler C, Pfeilschifter J, Frank S
Mol Med
. 2001 Jul;
6(12):1016-27.
PMID: 11474118
Background: Recently, we have reported a rapid and strong induction of interleukin-18 (IL-18) upon cutaneous injury in mice. In this paper, we investigated a possible role of IL-18 in triggering...
9.
Kampfer H, Muhl H, Manderscheid M, Kalina U, Kauschat D, Pfeilschifter J, et al.
Eur Cytokine Netw
. 2000 Dec;
11(4):626-33.
PMID: 11125306
Keratinocytes display a high basal level expression of IL-18. Tumor necrosis factor-alpha (TNF-alpha) mediated a large decrease in IL-18 mRNA levels in the human keratinocyte cell line HaCaT, which was...
10.
Muhl H, Chang J, Huwiler A, Bosmann M, Paulukat J, Ninic R, et al.
Free Radic Biol Med
. 2000 Nov;
29(10):969-80.
PMID: 11084285
Nitric oxide (NO) appears to act as an inflammatory mediator on monocytic cells. Exogenous NO augmented release of chemokines from human promonocytic U937 cells and peripheral blood mononuclear cells. Pharmacological...