H Mizuguchi
Overview
Explore the profile of H Mizuguchi including associated specialties, affiliations and a list of published articles.
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Articles
135
Citations
1505
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Recent Articles
21.
Kanehira M, Xin H, Hoshino K, Maemondo M, Mizuguchi H, Hayakawa T, et al.
Cancer Gene Ther
. 2007 Aug;
14(11):894-903.
PMID: 17693990
Most advanced solid tumors metastasize to different organs. However, no gene therapy effective for multiple tumors has yet been developed. Since a unique characteristic of bone marrow-derived mesenchymal stem cells...
22.
Kawabata K, Tashiro K, Sakurai F, Osada N, Kusuda J, Hayakawa T, et al.
Gene Ther
. 2007 Jun;
14(16):1199-207.
PMID: 17538635
Coxsackievirus and adenovirus receptor (CAR) is a member of the immunoglobulin (Ig) superfamily and a component of epithelial tight junction. CAR also functions as a primary receptor for coxsackievirus B...
23.
Kurachi S, Tashiro K, Sakurai F, Sakurai H, Kawabata K, Yayama K, et al.
Gene Ther
. 2007 May;
14(15):1160-5.
PMID: 17508008
The interaction between viral capsid proteins and specific molecules exposed on the plasma membrane of the cells is involved in the viral tropism. A human adenovirus (Ad) belonging to subgroups...
24.
Sakurai F, Akitomo K, Kawabata K, Hayakawa T, Mizuguchi H
Gene Ther
. 2007 Mar;
14(11):912-9.
PMID: 17377598
Human CD46 (membrane cofactor protein), which serves as a receptor for a variety of pathogens, including strains of measles virus, human herpesvirus type 6 and Neisseria, is rapidly downregulated from...
25.
Gao J, Kanagawa N, Motomura Y, Yanagawa T, Sugita T, Hatanaka Y, et al.
Gene Ther
. 2007 Jan;
14(6):491-502.
PMID: 17203106
Interleukin-12 (IL-12) is a potent antitumoral cytokine, but high doses are toxic. Herein, we demonstrate that combinational transduction of IL-12 and CC-chemokine ligand-27 (CCL27) genes into pre-existing murine OV-HM ovarian...
26.
Kurachi S, Koizumi N, Sakurai F, Kawabata K, Sakurai H, Nakagawa S, et al.
Gene Ther
. 2006 Sep;
14(3):266-74.
PMID: 17006548
Adenovirus (Ad) vectors are widely used in gene therapy and in vitro/in vivo gene transfer because of their high transduction efficiency. However, Ad vector application in the gene therapy field...
27.
Komiya E, Kondoh M, Mizuguchi H, Fujii M, Utoguchi N, Nakanishi T, et al.
Placenta
. 2006 Apr;
27(9-10):934-8.
PMID: 16600369
Nonviral gene delivery systems are useful for basic research in trophoblasts. In these systems, gene expression is regulated by a cassette of regulatory elements within the plasmid, and the transcriptional...
28.
Sakurai F, Kawabata K, Koizumi N, Inoue N, Okabe M, Yamaguchi T, et al.
Gene Ther
. 2006 Mar;
13(14):1118-26.
PMID: 16541121
We previously demonstrated that systemic administration of adenovirus serotype 35 (Ad35) vectors to mice does not mediate efficient transduction in organs, probably because expression of the mouse analog of the...
29.
Mizuguchi H, Mizuno H, Yasukawa K, Ishiguro T, Fukui K, Imanaka T, et al.
J Biosci Bioeng
. 2005 Oct;
91(3):299-304.
PMID: 16232993
In order to develop a new type of agonist for the interleukin 6 (IL-6) signal, the gene encoding a directly fused protein (DFP) was constructed by joining the N-terminal portion...
30.
Koizumi N, Kondoh M, Mizuguchi H, Nakanishi T, Masuyama A, Ida F, et al.
Placenta
. 2005 Oct;
26(10):729-34.
PMID: 16226122
The transfer of genes of interest is a useful method for studying placental biology. Recombinant adenovirus (Ad) vector is an efficient vector for transgene expression. An interaction between the fiber...