H Mizuguchi
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Explore the profile of H Mizuguchi including associated specialties, affiliations and a list of published articles.
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Articles
135
Citations
1505
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Recent Articles
11.
Mizuguchi H, Kitamura Y, Kondo Y, Kuroda W, Yoshida H, Miyamoto Y, et al.
Methods Find Exp Clin Pharmacol
. 2011 Jan;
32(10):745-8.
PMID: 21225011
Administration of antihistamines 2-4 weeks before the pollen season showed a greater inhibitory effect on nasal allergy symptoms in patients with seasonal allergic rhinitis. However, the mechanism of slow-onset effects...
12.
Umehara H, Mizuguchi H, Mizukawa N, Matsumoto M, Takeda N, Senba E, et al.
Methods Find Exp Clin Pharmacol
. 2011 Jan;
32(10):733-6.
PMID: 21225009
It has been well established that histaminergic neurons innervate densely the anterior hypothalamus and regulate several functions through the histamine H₁ receptor (H1R). However, the physiological function of the histaminergic...
13.
Watanabe Y, Kojima T, Kagawa S, Uno F, Hashimoto Y, Kyo S, et al.
Oncogene
. 2009 Nov;
29(8):1145-54.
PMID: 19935710
Malignant pleural mesothelioma (MPM) is a highly aggressive tumor that is related to asbestos exposure. MPM is characterized by rapid and diffuse local growth in the thoracic cavity, and it...
14.
Yao X, Yoshioka Y, Morishige T, Eto Y, Watanabe H, Okada Y, et al.
Gene Ther
. 2009 Jul;
16(12):1395-404.
PMID: 19641532
Cancer gene therapy by adenovirus vectors (Advs) for metastatic cancer is limited because systemic administration of Adv produces low therapeutic effect and severe side effects. In this study, we generated...
15.
Matsui H, Sakurai F, Kurachi S, Tashiro K, Sugio K, Kawabata K, et al.
Gene Ther
. 2009 Jun;
16(8):1050-7.
PMID: 19516278
Fiber-substituted adenovirus (Ad) vectors containing fibers of Ad serotype 35 (AdF35) efficiently transduce a variety of human cells because their receptor, human CD46, is ubiquitously expressed on almost all nucleated...
16.
Shimada M, Wang H, Kondo A, Xu X, Yoshida A, Shinoda K, et al.
Gene Ther
. 2008 Oct;
16(2):218-28.
PMID: 18923453
Antiretroviral therapy (ART) effectively slows the progression of AIDS. However, drug resistance and/or toxicity can limit the utility of ART in many patients. In this study, we assessed whether a...
17.
Sakurai F, Nakamura S, Akitomo K, Shibata H, Terao K, Kawabata K, et al.
Gene Ther
. 2008 Sep;
16(2):297-302.
PMID: 18800152
Adenovirus (Ad) serotype 35 (Ad35) vectors have attracted remarkable attention as alternatives to conventional Ad serotype 5 (Ad5) vectors. In a previous study, we showed that intravenously administered Ad35 vectors...
18.
Izumi N, Mizuguchi H, Umehara H, Ogino S, Fukui H
Methods Find Exp Clin Pharmacol
. 2008 Jul;
30(3):225-30.
PMID: 18597008
Sedation is the most frequent side effect of H(1)-antihistamines, and, sometimes, it may be life-threatening for patients. Evaluation of the sedative properties of H(1)-antihistamines is important to improve the patients'...
19.
Yoshikawa T, Niwa T, Mizuguchi H, Okada N, Nakagawa S
Gene Ther
. 2008 May;
15(19):1321-9.
PMID: 18480845
Dendritic cells (DCs) have a critical role in the induction of antigen-specific immune responses, transporting antigens from peripheral tissue to regional lymph nodes where they interact with antigen-specific T lymphocytes....
20.
Murakami S, Sakurai F, Kawabata K, Okada N, Fujita T, Yamamoto A, et al.
Gene Ther
. 2007 Sep;
14(21):1525-33.
PMID: 17805302
Most subgroup B adenoviruses (Ads), including adenovirus (Ad) serotype 35 (Ad35), bind to human CD46 as a receptor; however, the infection processes of subgroup B Ads following attachment to CD46...