H Mizuguchi
Overview
Explore the profile of H Mizuguchi including associated specialties, affiliations and a list of published articles.
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Articles
135
Citations
1505
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Recent Articles
1.
Wakabayashi K, Machitani M, Tachibana M, Sakurai F, Mizuguchi H
J Virol
. 2018 Oct;
93(2).
PMID: 30355689
The adenovirus (Ad) serotype 5 genome encodes two noncoding small RNAs (virus-associated RNAs I and II [VA-RNAI and -II]), which are approximately 160-nucleotide (nt) RNAs transcribed by RNA polymerase III....
2.
Ajani J, Abramov M, Bondarenko I, Shparyk Y, Gorbunova V, Hontsa A, et al.
Ann Oncol
. 2017 Sep;
28(9):2142-2148.
PMID: 28911091
Background: The effect of histology-based treatment regimen on diffuse gastric adenocarcinoma has not been evaluated in clinical trials. This international phase III trial evaluated the efficacy and safety of S-1...
3.
Longo-Munoz F, Argiles G, Tabernero J, Cervantes A, Gravalos C, Pericay C, et al.
Clin Transl Oncol
. 2016 Jul;
19(2):227-235.
PMID: 27443414
Purpose: TAS-102 is a combination of the thymidine-based nucleoside analog trifluridine and the thymidine phosphorylase inhibitor tipiracil. Efficacy and safety of TAS-102 in patients with metastatic colorectal cancer (mCRC) refractory...
4.
Machitani M, Sakurai F, Wakabayashi K, Nakatani K, Shimizu K, Tachibana M, et al.
Sci Rep
. 2016 Jan;
6:19922.
PMID: 26814140
The replication-incompetent adenovirus (Ad) vector is one of the most promising vectors for gene therapy; however, systemic administration of Ad vectors results in severe hepatotoxicities, partly due to the leaky...
5.
Terasawa Y, Hotani T, Katayama Y, Tachibana M, Mizuguchi H, Sakurai F
Cancer Gene Ther
. 2015 Jan;
22(4):188-97.
PMID: 25633482
Reovirus has gained much attention as an anticancer agent; however, the mechanism of the tumor cell-specific replication of reovirus is not fully understood. Although Ras activation is known to be...
6.
Shimano T, Terui K, Daibo M, Kanno T, Furukawa K, Yanagisawa T, et al.
Dentomaxillofac Radiol
. 2015 Jan;
4(1):66-7.
PMID: 25629863
No abstract available.
7.
Tagawa M, Shirane K, Yu L, Sato T, Furukawa S, Mizuguchi H, et al.
Cancer Gene Ther
. 2014 Jun;
21(6):219-27.
PMID: 24903013
Altered N-glycosylation of membrane proteins is associated with malignant transformation of cells. We found that the expression of the β4-galactosyltransferase 2 (β4GalT2) gene is decreased markedly during the transformation. Here,...
8.
Sakurai F, Nanjo Y, Okamoto S, Tachibana M, Mizuguchi H
Cancer Gene Ther
. 2014 Mar;
21(4):164-70.
PMID: 24651481
Recent studies have demonstrated that small double-stranded RNAs (dsRNAs) complementary to the promoter region of target genes enhance the expression of those genes following transfection into cells. Here we show...
9.
Machitani M, Sakurai F, Katayama K, Tachibana M, Suzuki T, Matsui H, et al.
Virus Res
. 2013 Sep;
178(2):357-63.
PMID: 24055658
Several studies have reported that short hairpin RNA (shRNA)-mediated RNA interference (RNAi) was competitively inhibited by the expression of adenovirus (Ad)-encoded small RNAs (VA-RNAs), which are expressed from a replication-incompetent...
10.
Iguchi K, Sakurai F, Tomita K, Katayama K, Yamaguchi T, Kawabata K, et al.
Cancer Gene Ther
. 2011 Nov;
19(2):118-25.
PMID: 22076042
Carrier cells delivering a conditionally replicating adenovirus (CRAd), which selectively replicates in tumor cells and induces tumor cell lysis, have promising potential for treatment of cancer because CRAd-loaded carrier cells...