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H Luss

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Articles 34
Citations 387
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Recent Articles
1.
Linck B, Boknik P, Knapp J, Kikuchi K, Luss H, Muller F, et al.
Mol Cell Biochem . 2001 Oct; 223(1-2):123-9. PMID: 11681713
The aim of this study was to investigate the functional properties of the promoter of the protein phosphatase 1alpha catalytic subunit. Luciferase plasmids with different fragments of the rat catalytic...
2.
Muller F, Boknik P, Knapp J, Linck B, Luss H, Neumann J, et al.
Cardiovasc Res . 2001 Sep; 52(1):95-102. PMID: 11557237
Objective: Chronic beta-adrenergic stimulation of the cAMP-dependent signalling pathway is implicated in functionally relevant expressional changes in congestive heart failure. We studied activation and inactivation of the cardiac gene transcription...
3.
Boknik P, Kirchhefer U, Knapp J, Linck B, Luss H, Muller T, et al.
Cardiovasc Res . 2001 Sep; 51(4):717-28. PMID: 11530105
Objective: Chronic pressure overload in spontaneously hypertensive rats (SHR) is accompanied by heart hypertrophy and signs of heart failure. Since there is growing evidence for a possible pathophysiological role of...
4.
Schulz R, Post H, Neumann T, Gres P, Luss H, Heusch G
Am J Physiol Heart Circ Physiol . 2001 Apr; 280(5):H1945-53. PMID: 11299193
It is unclear whether perfusion-contraction matching (PCM) is maintained during prolonged myocardial ischemia. In 27 anesthetized pigs, left anterior descending coronary arterial inflow was reduced to decrease an anterior work...
5.
Boknik P, Khorchidi S, Bodor G, Huke S, Knapp J, Linck B, et al.
Am J Physiol Heart Circ Physiol . 2001 Feb; 280(2):H786-94. PMID: 11158978
We studied the effects of the protein phosphatase (PP) inhibitor cantharidin (Cant) on time parameters and force of contraction (FOC) in isometrically contracting electrically driven guinea pig papillary muscles. We...
6.
Luss H, Klein-Wiele O, Boknik P, Herzig S, Knapp J, Linck B, et al.
J Mol Cell Cardiol . 2000 Dec; 32(12):2349-59. PMID: 11113010
In mammalian species, including man, the duration of myocardial contraction is shorter in atria than ventricles. Total contraction time depends at least in part on phosphorylation and dephosphorylation of cardiac...
7.
Luss H, Neumann J, Schmitz W, Schulz R, Heusch G
J Mol Cell Cardiol . 2000 Oct; 32(10):1787-94. PMID: 11013123
Stress-responsive p38 MAP kinase is activated by phosphorylation during global and severe regional myocardial ischemia. However, it is unknown whether or not moderate, low-flow ischemia also activates p38 MAP kinase....
8.
Boknik P, Fockenbrock M, Herzig S, Knapp J, Linck B, Luss H, et al.
Naunyn Schmiedebergs Arch Pharmacol . 2000 Sep; 362(3):222-31. PMID: 10997724
We tested the hypothesis that altered phosphorylation of Ca2+ regulatory proteins contributes to contractile anomalies in cardiac hypertrophy. Cardiac hypertrophy was induced in rats by chronic s.c. administration of isoproterenol...
9.
Linck B, Boknik P, Huke S, Kirchhefer U, Knapp J, Luss H, et al.
J Pharmacol Exp Ther . 2000 Jul; 294(2):648-57. PMID: 10900244
Overexpression of calsequestrin (CSQ) induces severe cardiac hypertrophy, whereas overexpression of Na(+)-Ca(2+) exchanger (NCX) does not affect cardiac weight. To investigate a possible beneficial effect of NCX in hypertrophy, we...
10.
Knapp J, Boknik P, Linck B, Luss H, Muller F, Petertonjes L, et al.
J Pharmacol Exp Ther . 2000 Jul; 294(2):620-6. PMID: 10900240
In this study we characterized the effects of the protein phosphatase (PP) type 1 and type 2A inhibitor cantharidin (Cant) and its structural analogs cantharidic acid and endothall on PP...