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H Leon Bradlow

Explore the profile of H Leon Bradlow including associated specialties, affiliations and a list of published articles. Areas
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Articles 31
Citations 536
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Recent Articles
1.
Telang N, Li G, Katdare M, Sepkovic D, Bradlow H, Wong G
Oncol Lett . 2017 Apr; 13(4):2477-2482. PMID: 28454423
The Luminal A subtype of breast cancer expresses the estrogen receptor (ER)-α and progesterone receptor (PR), but not the human epidermal growth factor receptor (HER)-2 oncogene. This subtype of breast...
2.
Nikitina D, Llacuachaqui M, Sepkovic D, Bradlow H, Narod S, Kotsopoulos J
Fam Cancer . 2015 Jan; 14(2):281-6. PMID: 25613194
Hormonal exposures are known to influence breast cancer risk among women with a BRCA1 mutation. Thus, dietary factors that increase the 2-hydroxyestrone (OHE):16α-OHE ratio, a biomarker inversely related to breast...
3.
Bradlow H
Horm Mol Biol Clin Investig . 2014 Nov; 17(1):53-61. PMID: 25372730
While there is a large volume of literature describing a role for obesity as a risk factor for breast cancer and many other cancers, in the main a causal relationship...
4.
Telang N, Li G, Sepkovic D, Bradlow H, Wong G
Nutr Cancer . 2014 Jan; 66(2):278-84. PMID: 24377707
Chemo-endocrine therapy for estrogen receptor positive (ER(+)) breast cancer exhibits acquired tumor resistance. Herbal medicines provide integrative support for breast cancer patients. Present study compared the efficacy of aqueous extracts...
5.
Sepkovic D, Pagan D, Stein J, Carlisle A, Ksieski H, Auborn K, et al.
In Vivo . 2013 Apr; 27(3):299-304. PMID: 23606684
Background: The effects of 3,3'-diindolylmethane (DIM) together with the Gardasil vaccine on cervical histology were evaluated using the K14-HPV16-transgenic mouse model. The possibility that DIM could enhance the efficacy of...
6.
Persky V, Piorkowski J, Turyk M, Freels S, Chatterton Jr R, Dimos J, et al.
Environ Health . 2012 Aug; 11:57. PMID: 22931295
Background: Studies have shown associations of diabetes and endogenous hormones with exposure to a wide variety of organochlorines. We have previously reported positive associations of polychlorinated biphenyls (PCBs) and inverse...
7.
Sepkovic D, Raucci L, Stein J, Carlisle A, Auborn K, Ksieski H, et al.
In Vivo . 2012 Feb; 26(2):207-11. PMID: 22351660
Unlabelled: While cervical cancer incidence and mortality rates have declined in the United States, this cancer represents a worldwide threat. Human papilloma viral infection causes cervical neoplasia (CIN). 3,3'-Diindolylmethane (DIM)...
8.
Bradlow H, Sepkovic D, Telang N, Tiwari R
In Vivo . 2011 Jun; 25(4):585-8. PMID: 21709000
The role of body fat as a risk factor for breast cancer has been well established. A decrease in the urinary 2/16α-hydroxyestrone ratio has also been shown to be a...
9.
Persky V, Piorkowski J, Turyk M, Freels S, Chatterton Jr R, Dimos J, et al.
Environ Res . 2011 Jun; 111(6):817-24. PMID: 21684538
There is an increasing body of literature showing associations of organochlorine exposure with risk of diabetes and insulin resistance. Some studies suggest that associations differ by gender and that diabetes...
10.
Sepkovic D, Stein J, Carlisle A, Ksieski H, Auborn K, Raucci L, et al.
Cancer Prev Res (Phila) . 2011 Mar; 4(6):890-6. PMID: 21383027
The human papilloma virus is the major cause of cervical cancer. Viral infection initiates cervical intraepithelial neoplasia, which progresses through several stages to cervical cancer. The objective of this study...