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H Kosugi

Explore the profile of H Kosugi including associated specialties, affiliations and a list of published articles. Areas
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Articles 48
Citations 951
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Recent Articles
1.
Kosugi H, Kojima T, Kikugawa K
Lipids . 2016 Aug; 24(10):873-81. PMID: 27520441
The thiobarbituric acid (TBA) reaction was performed on linoleic acid 13-monohydroperoxide, autoxidized fatty esters, edible fats and oils, rat liver microsomal lipids, and on human erythrocyte ghost lipids in order...
2.
Tomiyama Y, Miyakawa Y, Okamoto S, Katsutani S, Kimura A, Okoshi Y, et al.
J Thromb Haemost . 2012 Mar; 10(5):799-806. PMID: 22409309
Background: Eltrombopag is an oral, non-peptide thrombopoietin receptor agonist that has shown efficacy and safety in chronic immune thrombocytopenia (ITP). However, ethnic differences in eltrombopag exposure have been reported: area...
3.
Miyazaki K, Yamaguchi M, Suzuki R, Kobayashi Y, Maeshima A, Niitsu N, et al.
Ann Oncol . 2011 Jan; 22(7):1601-1607. PMID: 21199885
Background: CD5-positive (CD5+) diffuse large B-cell lymphoma (DLBCL) shows poor prognosis and frequent central nervous system (CNS) relapses under anthracycline-containing chemotherapy. The aim of this study was to determine the...
4.
Kawarabayasi Y, Hino Y, Horikawa H, Takahashi M, Sekine M, Baba S, et al.
DNA Res . 2001 Sep; 8(4):123-40. PMID: 11572479
The complete genomic sequence of an aerobic thermoacidophilic crenarchaeon, Sulfolobus tokodaii strain7 which optimally grows at 80 degrees C, at low pH, and under aerobic conditions, has been determined by...
5.
Kosugi H, Yamamoto Y, Towatari M, Ito M, Ueda R, Saito H, et al.
Jpn J Cancer Res . 2001 May; 92(5):529-36. PMID: 11376562
Histone acetylation and deacetylation are closely linked to transcriptional activation and repression, respectively. In acute promyelocytic leukemia (APL), histone deacetylase inhibitors (HDACIs) have a synergistic effect with all-trans retinoic acid...
6.
Murata M, Towatari M, Kosugi H, Tanimoto M, Ueda R, Saito H, et al.
Jpn J Cancer Res . 2000 Nov; 91(11):1154-60. PMID: 11092981
Histone deacetylases are promising targets for cancer treatment. Here we studied the in vitro effects of a potent histone deacetylase inhibitor, FK228 (formerly FR901228), on human leukemia / lymphoma cells...
7.
Maeda T, Towatari M, Kosugi H, Saito H
Blood . 2000 Nov; 96(12):3847-56. PMID: 11090069
Histone deacetylase inhibitors (HDACIs) have been used to focus on the effects of inducing gene expression through the acetylation of histones which results in chromatin remodeling. The study explored whether...
8.
Tomita A, Towatari M, Tsuzuki S, Hayakawa F, Kosugi H, Tamai K, et al.
Oncogene . 2000 Feb; 19(3):444-51. PMID: 10656693
Transcription factor c-Myb plays important roles in cell survival and differentiation in immature hematopoietic cells. Here we demonstrate that c-Myb is acetylated at the carboxyl-terminal conserved domain by histone acetyltransferase...
9.
Nakamura M, Yagi H, Endo Y, Kosugi H, Ishi T, Itoh T
Br J Haematol . 1999 Dec; 107(4):779-90. PMID: 10606885
We previously showed that aminobisphosphonates (aminoBPs), potent inhibitors of bone resorption, increased the number of osteoclasts and granulocytes, and enhanced the cell size of osteoclasts in vivo, indicating that aminoBPs...
10.
NARUMI J, Miyazawa S, Miyata H, Suzuki A, Kohsaka S, Kosugi H
Accid Anal Prev . 1999 Sep; 31(6):625-9. PMID: 10487337
Analysis of reports about incidental and accidental events in nursing care were made using a reliability engineering method. Unnatural working hours, such as evening duty, night duty falling next to...