H J Klimisch
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Explore the profile of H J Klimisch including associated specialties, affiliations and a list of published articles.
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47
Citations
273
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Recent Articles
1.
Klimisch H, Hellwig J
Hum Exp Toxicol
. 2001 Apr;
19(12):676-83.
PMID: 11291739
(1) Dimethylacetamide was tested for developmental toxicity after inhalation exposure of pregnant Himalayan rabbits. Fifteen female rabbits per main group were exposed to dimethylacetamide vapours at concentrations of 0, 0.2,...
2.
Ruckman S, Green O, Palmer A, Klimisch H
Toxicol Lett
. 1999 Jun;
105(3):231-7.
PMID: 10355544
To assess the prenatal toxicity to rats of the anti-foaming agent, tri-isobutylphosphate (CAS 126-71-6), a study was conducted in which daily dosages of 0, 100, 300 and 1000 mg/kg were...
3.
Klimisch H, Deckardt K, Gembardt C, Hildebrand B
Food Chem Toxicol
. 1998 Jun;
36(3):165-8.
PMID: 9609389
A 90-day subchronic inhalation toxicity study was performed on Wistar rats in accordance to OECD testing guidelines to evaluate the toxicological profile of 2-ethylhexanol, potential target organs, and a no-observable-adverse-effect-level...
4.
Greim H, Bury D, Klimisch H, Ziegler-Skylakakis K
Chemosphere
. 1998 May;
36(2):271-95.
PMID: 9569935
SARs may enable the evaluation of the toxic potential of chemicals by drawing conclusions from available data on structurally-related chemicals, thus reducing the need for further testing. The Advisory Committee...
5.
Klimisch H, Deckardt K, Gembardt C, Hildebrand B, Kuttler K, Roe F
Food Chem Toxicol
. 1998 Feb;
35(10-11):1061-74.
PMID: 9463540
N-Vinylpyrrolidone-2 (NVP) is a monomeric compound used as an industrial intermediate. Nine of 11 studies previously reported involved exposure of rats (two different strains), mice or hamsters to NVP by...
6.
Klimisch H, Deckardt K, Gembardt C, Hildebrand B, Kuttler K, Roe F
Food Chem Toxicol
. 1998 Feb;
35(10-11):1041-60.
PMID: 9463539
In previous subchronic studies inhaled N-vinylpyrrolidone-2 (NVP) was haemotoxic, hepatotoxic and irritant to the nose. In the first of two long-term studies, study A, Sprague-Dawley rats were exposed by inhalation...
7.
Schilling K, Kayser M, Deckardt K, Kuttler K, Klimisch H
Hum Exp Toxicol
. 1998 Jan;
16(12):722-6.
PMID: 9429086
1. 90-day subchronic toxicity studies with 3-methyl-1-butanol (MEB) and 2-methyl-1-propanol (MEP) were performed on rats to evaluate the toxicological profile of the compounds under conditions of drinking water studies, to...
8.
Hellwig J, Beth M, Klimisch H
Toxicol Lett
. 1997 Aug;
92(3):221-30.
PMID: 9334833
Developmental toxicity of 2-butin-1,4-diol was determined in groups of 18-22 pregnant Wistar rats at dose levels of 10, 40 and 80 mg/kg bw/day administered by gavage from days 6 to...
9.
Hardy C, Coombs D, Lewis D, Klimisch H
Fundam Appl Toxicol
. 1997 Aug;
38(2):143-7.
PMID: 9299187
This study was carried out to provide information on the effects of inhalation of diethylene glycol monoethyl ether, a substance used in industry which may be accidentally inhaled by man....
10.
Hellwig J, Klimisch H
Food Chem Toxicol
. 1997 Jul;
35(7):677-81.
PMID: 9301651
Developmental toxicity of isobutylidenediurea (IBDU) was determined by oral administration to Wistar rats. The substance was administered as an aqueous suspension to 22-24 pregnant rats per group by gavage in...