H Hottinger
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Explore the profile of H Hottinger including associated specialties, affiliations and a list of published articles.
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22
Citations
389
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Recent Articles
1.
Hottinger H, Leupold U
Curr Genet
. 2013 Nov;
3(2):133-43.
PMID: 24190059
Nine genetically distinct suppressors of ICR-170-induced ade6 and ade7 mutations have been identified in Schizosaccharomyces pombe. The nine suppressors of ICR-170-induced and spontaneous origin have been assigned to the three...
2.
Kochhar S, Lamzin V, Razeto A, Delley M, Hottinger H, Germond J
Eur J Biochem
. 2000 Mar;
267(6):1633-9.
PMID: 10712593
The role of three histidine residues (His205, His296 and His303) and Asp259, important for the catalysis of NAD+-specific D-lactate dehydrogenase, was investigated using site-directed mutagenesis. None of these residues is...
3.
Oliver S, Hottinger H, Soll D
Biochimie
. 1994 Jan;
76(1):45-9.
PMID: 8031904
The nifS gene was first identified in nitrogen-fixing bacteria where its protein product is essential for efficient nitrogen fixation. Here, we demonstrate that a nifS-like gene also occurs in Lactobacillus...
4.
Kochhar S, Chuard N, Hottinger H
J Biol Chem
. 1992 Oct;
267(28):20298-301.
PMID: 1356978
Recently, we amplified the Lactobacillus bulgaricus NAD(+)-dependent D-lactate dehydrogenase gene by the polymerase chain reaction, cloned and overexpressed it in Escherichia coli (Kochhar, S., Chuard, N., and Hottinger, H. (1992)...
5.
Kochhar S, Hottinger H, Chuard N, Taylor P, Atkinson T, Scawen M, et al.
Eur J Biochem
. 1992 Sep;
208(3):799-805.
PMID: 1396685
NAD(+)-dependent D-lactate dehydrogenase from Lactobacillus helveticus was purified to apparent homogeneity, and the sequence of the first 36 amino acid residues determined. Using forward and reverse oligonucleotide primers, based on...
6.
Ishino Y, MORGENTHALER P, Hottinger H, Soll D
Appl Environ Microbiol
. 1992 Sep;
58(9):3165-9.
PMID: 1359838
A 3.3-kb BamHI fragment of Lactobacillus delbrueckii subsp. bulgaricus DNA was cloned and sequenced. It complements an Escherichia coli glnA deletion strain and hybridizes strongly to a DNA containing the...
7.
Kochhar S, Chuard N, Hottinger H
Biochem Biophys Res Commun
. 1992 Jun;
185(2):705-12.
PMID: 1610363
The Lactobacillus bulgaricus NAD(+)-dependent D-lactate dehydrogenase gene was amplified by the polymerase chain reaction and cloned into an Escherichia coli expression plasmid pKK223.3. Attempts to clone the full-length chromosomal DNA...
8.
Kochhar S, Hunziker P, Hottinger H
J Biol Chem
. 1992 Apr;
267(12):8499-513.
PMID: 1569100
The NAD(+)-dependent D-lactate dehydrogenase was purified to apparent homogeneity from Lactobacillus bulgaricus and its complete amino acid sequence determined. Two gaps in the polypeptide chain (10 residues) were filled by...
9.
Kochhar S, Hunziker P, Hottinger H
Biochem Biophys Res Commun
. 1992 Apr;
184(1):60-6.
PMID: 1567457
A comparison of the primary structures of NAD(+)-dependent D-lactate dehydrogenase with L-lactate dehydrogenase and L-malate dehydrogenase failed to show any sequence similarity. However, D-2-hydroxyisocaproate dehydrogenase from Lactobacillus casei, glycerate dehydrogenase...
10.
Zwahlen M, Hottinger H
J Bacteriol
. 1991 Mar;
173(6):1951-7.
PMID: 1705929
The genes coding for the lactose permease and beta-galactosidase, two proteins involved in the metabolism of lactose by Lactobacillus bulgaricus, have been cloned, expressed, and found functional in Escherichia coli....