H C Whitaker
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Explore the profile of H C Whitaker including associated specialties, affiliations and a list of published articles.
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7
Citations
156
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Recent Articles
1.
Whitaker H, Shiong L, Kay J, Gronberg H, Warren A, Seipel A, et al.
Oncogene
. 2013 Nov;
33(45):5274-87.
PMID: 24240687
N-acetyl-L-aspartyl-L-glutamate peptidase-like 2 (NAALADL2) is a member of the glutamate carboxypeptidase II family, best characterized by prostate-specific membrane antigen (PSMA/NAALAD1). Using immunohistochemistry (IHC), we have shown overexpression of NAALADL2 in...
2.
Whitaker H, Patel D, Howat W, Warren A, Kay J, Sangan T, et al.
Br J Cancer
. 2013 Jul;
109(4):983-93.
PMID: 23880827
Objective: We have previously identified peroxiredoxin-3 (PRDX-3) as a cell-surface protein that is androgen regulated in the LNCaP prostate cancer (PCa) cell line. PRDX-3 is a member of the peroxiredoxin...
3.
Girling J, Whitaker H, Mills I, Neal D
Indian J Urol
. 2009 Aug;
23(1):35-42.
PMID: 19675761
Prostate cancer is the second most common malignancy in males and the leading cause of cancer death. Prostate cancer is initially androgen dependent and relies upon the androgen receptor (AR)...
4.
Thirkettle H, Mills I, Whitaker H, Neal D
Oncogene
. 2009 Aug;
28(41):3663-70.
PMID: 19648967
LYRIC/AEG-1 and its altered expression have been linked to carcinogenesis in prostate, brain and melanoma as well as promoting chemoresistance and metastasis in breast cancer. LYRIC/AEG-1 function remains unclear, although...
5.
Deeb A, Jaaskelainen J, Dattani M, Whitaker H, Costigan C, Hughes I
J Clin Endocrinol Metab
. 2008 Aug;
93(10):3691-6.
PMID: 18697867
Context: The androgen insensitivity syndrome (AIS) is caused by molecular defects in the androgen receptor (AR). Clinically, the partial AIS has a variable phenotype. Many mechanisms explain the phenotype in...
6.
Powell S, Brooke G, Whitaker H, Reebye V, Gamble S, Chotai D, et al.
Biochem Soc Trans
. 2006 Nov;
34(Pt 6):1124-7.
PMID: 17073766
Anti-androgens used in prostate cancer therapy inhibit AR (androgen receptor) activity via largely unknown mechanisms. Although initially successful in most cases, they eventually fail and the disease progresses. We need...
7.
Roobol A, Grantham J, Whitaker H, Carden M
J Biol Chem
. 1999 Jun;
274(27):19220-7.
PMID: 10383429
The eukaryotic, cytoplasmic chaperonin, CCT, is essential for the biogenesis of actin- and tubulin-based cytoskeletal structures. CCT purifies as a doubly toroidal particle containing two eight-membered rings of approximately 60-kDa...