H Blaak
Overview
Explore the profile of H Blaak including associated specialties, affiliations and a list of published articles.
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Articles
16
Citations
599
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Recent Articles
1.
Blaak H, Boers P, Gruters R, Schuitemaker H, van der Ende M, Osterhaus A
J Virol
. 2005 Jan;
79(3):1686-700.
PMID: 15650194
Human immunodeficiency virus type 2 (HIV-2) is generally considered capable of using a broad range of coreceptors. Since HIV-2 variants from individuals with nonprogressive infection were not studied previously, the...
2.
van Rij R, Blaak H, Visser J, Brouwer M, Rientsma R, Broersen S, et al.
J Clin Invest
. 2000 Oct;
106(8):1039-52.
PMID: 11032864
We demonstrated previously that CD45RA(+) CD4(+) T cells are infected primarily by syncytium-inducing (SI) HIV-1 variants, whereas CD45RO(+) CD4(+) T cells harbor both non-SI (NSI) and SI HIV-1 variants. Here,...
3.
Kostense S, Krop E, Blaak H, Schuitemaker H, Miedema F
AIDS
. 2000 Mar;
14(3):330-1.
PMID: 10716514
No abstract available.
4.
Blaak H, Ran L, Rientsma R, Schuitemaker H
Virology
. 2000 Feb;
267(2):237-46.
PMID: 10662619
Susceptibility of PHA/rIL-2-stimulated PBMC from 14 healthy blood donors for NSI HIV-1 infection was analyzed in relation to CCR5 expression and beta-chemokine production. After 1 week of culture in the...
5.
Blaak H, vant Wout A, Brouwer M, Hooibrink B, Hovenkamp E, Schuitemaker H
Proc Natl Acad Sci U S A
. 2000 Feb;
97(3):1269-74.
PMID: 10655520
Switch from non-syncytium-inducing (NSI) to syncytium-inducing (SI) HIV type 1 (HIV-1) is associated with accelerated CD4(+) T cell depletion, which might partially be explained by higher virulence of SI variants...
6.
Prins J, Jurriaans S, van Praag R, Blaak H, van Rij R, Schellekens P, et al.
AIDS
. 1999 Dec;
13(17):2405-10.
PMID: 10597782
Background: A stable reservoir of latently infected, resting CD4 T cells has been demonstrated in HIV-1-infected patients despite prolonged antiretroviral treatment. This is a major barrier for the eradication of...
7.
de Roda Husman A, Blaak H, Brouwer M, Schuitemaker H
J Immunol
. 1999 Oct;
163(8):4597-603.
PMID: 10510404
CCR5 cell-surface expression was studied in relation to CCR5 genotype and clinical course of HIV-1 infection. HIV-1 infected CCR5+/+ individuals had higher percentages of CCR5-expressing CD4+ T cells as compared...
8.
de Roda Husman A, van Rij R, Blaak H, Broersen S, Schuitemaker H
J Infect Dis
. 1999 Sep;
180(4):1106-15.
PMID: 10479137
Fifty percent of individuals infected with human immunodeficiency virus type 1 (HIV-1) progress to AIDS in the presence of only non-syncytium-inducing (NSI) variants. These rapidly replicating NSI isolates are associated...
9.
van t Wout A, Blaak H, Ran L, Brouwer M, Kuiken C, Schuitemaker H
J Virol
. 1998 May;
72(6):5099-107.
PMID: 9573281
To investigate the temporal relationship between human immunodeficiency virus type 1 (HIV-1) replicative capacity and syncytium-inducing (SI) phenotype, biological and genetic characteristics of longitudinally obtained virus clones from two HIV-1-infected...
10.
Blaak H, Brouwer M, Ran L, de Wolf F, Schuitemaker H
J Infect Dis
. 1998 Mar;
177(3):600-10.
PMID: 9498438
In 7 long-term survivors (LTS) and 8 progressors, all carrying solely non-syncytium-inducing variants, a possible correlation between in vitro virus replicative capacity, virus load, and clinical course of human immunodeficiency...