H B Shu
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Explore the profile of H B Shu including associated specialties, affiliations and a list of published articles.
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16
Citations
2103
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Recent Articles
1.
Lwin T, Crespo L, Wu A, Dessureault S, Shu H, Moscinski L, et al.
Leukemia
. 2008 Oct;
23(1):170-7.
PMID: 18843286
This study explores whether lymphoma cell adhesion-induced B cell-activating factor (BAFF) expression in bone marrow stromal cells (BMSCs) protects B lymphoma cells from apoptosis. We first showed protection of lymphoma...
2.
Hu W, Johnson H, Shu H
J Biol Chem
. 2001 Feb;
275(15):10838-44.
PMID: 10753878
Fas-associated death domain protein (FADD), caspase-8-related protein (Casper), and caspase-8 are components of the tumor necrosis factor receptor type 1 (TNF-R1) and Fas signaling complexes that are involved in TNF-R1-...
3.
Shu H, Johnson H
Proc Natl Acad Sci U S A
. 2000 Jul;
97(16):9156-61.
PMID: 10908663
TALL-1 is a recently identified member of the tumor necrosis factor (TNF) family that costimulates B lymphocyte proliferation. Here we show that B cell maturation protein (BCMA), a member of...
4.
Yeh W, Itie A, Elia A, Ng M, Shu H, Wakeham A, et al.
Immunity
. 2000 Jul;
12(6):633-42.
PMID: 10894163
Casper (c-FLIP) associates with FADD and caspase-8 in signaling complexes downstream of death receptors like Fas. We generated Casper-deficient mice and cells and noted a duality in the physiological functions...
5.
Hu W, Johnson H, Shu H
J Biol Chem
. 1999 Oct;
274(43):30603-10.
PMID: 10521444
Tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) is a member of the TNF family that interacts with several receptors, including TRAIL-R1, TRAIL-R2, and TRAIL-R4. TRAIL-R1 and TRAIL-R2 can induce apoptosis...
6.
Shu H, Hu W, Johnson H
J Leukoc Biol
. 1999 May;
65(5):680-3.
PMID: 10331498
Members of the tumor necrosis factor (TNF) family play important roles in modulation of immune responses. We describe the identification and cloning of a novel TNF family member that has...
7.
Yeh W, de la Pompa J, McCurrach M, Shu H, Elia A, Shahinian A, et al.
Science
. 1998 Apr;
279(5358):1954-8.
PMID: 9506948
FADD (also known as Mort-1) is a signal transducer downstream of cell death receptor CD95 (also called Fas). CD95, tumor necrosis factor receptor type 1 (TNFR-1), and death receptor 3...
8.
Shu H, Halpin D, Goeddel D
Immunity
. 1997 Jun;
6(6):751-63.
PMID: 9208847
Caspases are cysteine proteases that play a central role in apoptosis. Caspase-8 may be the first enzyme of the proteolytic cascade activated by the Fas ligand and tumor necrosis factor...
9.
Shu H, Takeuchi M, Goeddel D
Proc Natl Acad Sci U S A
. 1996 Nov;
93(24):13973-8.
PMID: 8943045
The two cell surface receptors for tumor necrosis factor (TNF) interact with a number of intracellular signal transducing proteins. The association of TRADD, a 34-kDa cytoplasmic protein containing a C-terminal...
10.
Rothe M, Xiong J, Shu H, Williamson K, Goddard A, Goeddel D
Proc Natl Acad Sci U S A
. 1996 Aug;
93(16):8241-6.
PMID: 8710854
Tumor necrosis factor (TNF) receptor-associated factor (TRAF) proteins associate with and transduce signals from TNF receptor 2, CD40, and presumably other members of the TNF receptor superfamily. TRAF2 is required...