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Gyu-Sang Hong

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Articles 19
Citations 252
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Recent Articles
1.
Mun J, Jang M, Kim W, Kim S, Lee B, Moon H, et al.
ACS Chem Neurosci . 2025 Feb; 16(5):826-843. PMID: 39976589
Gold nanoparticles (AuNPs) are valuable tools in pharmacological and biological research, offering unique properties for drug delivery in the treatment of neurodegenerative diseases. This study investigates the potential of gold...
2.
Ha T, Kang B, Kim M, Chu J, Kim K, Yoon W, et al.
J Ethnopharmacol . 2024 Oct; 337(Pt 2):118869. PMID: 39353479
Ethnopharmacological Relevance: Uncaria rhynchophylla (UR) is recognized for its therapeutic applications in treating hypertension and inflammation. However, the specific molecular mechanisms how UR and its bioactive constituents modulate inflammatory pathways...
3.
Lee P, Ha T, Choi H, Lee S, Kim C, Hong G
Acta Physiol (Oxf) . 2024 Sep; 240(11):e14236. PMID: 39324481
Aim: This investigation addresses Piezo1's expression and mechanistic role in dorsal root ganglion (DRG) neurons and delineates its participation in mechanical and inflammatory pain modulation. Methods: We analyzed Piezo1's expression...
4.
Pak S, Ryu H, Lim S, Nguyen T, Yang S, Kang S, et al.
Cell Rep . 2024 Jun; 43(6):114334. PMID: 38850532
Mechanically activating (MA) channels transduce numerous physiological functions. Tentonin 3/TMEM150C (TTN3) confers MA currents with slow inactivation kinetics in somato- and barosensory neurons. However, questions were raised about its role...
5.
Kim H, Kang B, Lee P, Kim K, Hong G
Brain Struct Funct . 2024 Feb; 229(3):759-773. PMID: 38411929
Malformation during cortical development can disrupt the balance of excitatory and inhibitory neural circuits, contributing to various psychiatric and developmental disorders. One of the critical factors of cortical neural networks...
6.
Jeong S, Kang H, Kim S, Hong G, Nam M, Seong J, et al.
Sci Adv . 2023 Mar; 9(10):eadf0925. PMID: 36897938
Anisotropically organized neural networks are indispensable routes for functional connectivity in the brain, which remains largely unknown. While prevailing animal models require additional preparation and stimulation-applying devices and have exhibited...
7.
Kim H, Kim H, Nguyen L, Ha T, Lim S, Kim K, et al.
Prog Neurobiol . 2022 Nov; 219:102369. PMID: 36330924
Sensing smells of foods, prey, or predators determines animal survival. Olfactory sensory neurons in the olfactory epithelium (OE) detect odorants, where cAMP and Ca play a significant role in transducing...
8.
Ha T, Kim M, Kang B, Kim K, Hong S, Kang T, et al.
J Agric Food Chem . 2022 Mar; 70(13):3969-3978. PMID: 35343690
Several studies have documented the broad-spectrum bioactivities of a lotus seed ( [PN]) green embryo extract. However, the specific bioactive components and associated molecular mechanisms remain largely unknown. This study...
9.
Wee J, Pak S, Kim T, Hong G, Lee J, Nan J, et al.
Cell Rep . 2021 Dec; 37(9):110067. PMID: 34852221
Glucose homeostasis is initially regulated by the pancreatic hormone insulin. Glucose-stimulated insulin secretion in β-cells is composed of two cellular mechanisms: a high glucose concentration not only depolarizes the membrane...
10.
Lu H, Nguyen T, Hong G, Pak S, Kim H, Kim H, et al.
J Clin Invest . 2020 Jun; 130(7):3671-3683. PMID: 32484458
The baroreceptor reflex is a powerful neural feedback that regulates arterial pressure (AP). Mechanosensitive channels transduce pulsatile AP to electrical signals in baroreceptors. Here we show that tentonin 3 (TTN3/TMEM150C),...