Gyeoung-Jin Kang
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Explore the profile of Gyeoung-Jin Kang including associated specialties, affiliations and a list of published articles.
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34
Citations
348
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Recent Articles
1.
Xie A, Kang G, Kim E, Liu H, Feng F, Dudley Jr S
Circ Arrhythm Electrophysiol
. 2024 Aug;
17(10):e013054.
PMID: 39212055
Background: Increased mitochondrial Ca uptake has been implicated in the QT prolongation and lethal arrhythmias associated with nonischemic cardiomyopathy. We attempted to define the role of mitochondria in ischemic arrhythmic...
2.
Zhou X, Liu H, Feng F, Kang G, Liu M, Guo Y, et al.
JCI Insight
. 2024 Jun;
9(15).
PMID: 38889387
Diabetes mellitus (DM) is an independent risk factor for atrial fibrillation (AF). The mechanisms underlying DM-associated AF are unclear. AF and DM are both related to inflammation. We investigated whether...
3.
Xie A, Kang G, Kim E, Feng F, Givens S, Ogle B, et al.
PNAS Nexus
. 2023 Jun;
2(6):pgad174.
PMID: 37303713
Automaticity involves Ca handling at the cell membrane and sarcoplasmic reticulum (SR). Abnormal or acquired automaticity is thought to initiate ventricular arrhythmias associated with myocardial ischemia. Ca flux from mitochondria...
4.
Liu M, Kang G, Dudley Jr S
Trends Mol Med
. 2023 Jun;
29(8):583.
PMID: 37277278
No abstract available.
5.
Liu H, Huang Y, Zhao Y, Kang G, Feng F, Wang X, et al.
JACC Basic Transl Sci
. 2023 Mar;
8(2):174-185.
PMID: 36908663
Diabetes mellitus (DM) is a main risk factor for diastolic dysfunction (DD) and heart failure with preserved ejection fraction. High-fat diet (HFD) mice presented with diabetes mellitus, DD, higher cardiac...
6.
Kang G, Xie A, Kim E, Dudley Jr S
Heart Rhythm
. 2023 Jan;
20(5):730-736.
PMID: 36693615
Background: MicroRNA miR-448 mediates some of the effects of ischemia on arrhythmic risk. Potassium voltage-gated channel subfamily A member 4 (KCNA4) encodes a K1.4 current that opens in response to...
7.
Xie A, Liu H, Kang G, Feng F, Dudley Jr S
Heart Rhythm
. 2022 Aug;
19(12):2107-2114.
PMID: 36028211
Background: We have described an arrhythmic mechanism seen only in cardiomyopathy that involves increased mitochondrial Ca handling and selective transfer of Ca to the sarcoplasmic reticulum (SR). Modeling suggested that...
8.
Liu M, Kang G, Dudley Jr S
Trends Mol Med
. 2022 Apr;
28(6):443-451.
PMID: 35414478
Cardiomyopathies are associated with arrhythmias and cardiac ion channel downregulation. This downregulation is arrhythmogenic. Paradoxically, antiarrhythmic therapies are based on ion channel-blocking drugs that further downregulate these channels and exhibit...
9.
Liu M, Liu H, Parthiban P, Kang G, Shi G, Feng F, et al.
J Clin Invest
. 2021 Jul;
131(18).
PMID: 34324437
Ischemic cardiomyopathy is associated with an increased risk of sudden death, activation of the unfolded protein response (UPR), and reductions in multiple cardiac ion channels. When activated, the protein kinase-like...
10.
Liu M, Liu H, Feng F, Xie A, Kang G, Zhao Y, et al.
J Am Heart Assoc
. 2021 Jun;
10(12):e020205.
PMID: 34096318
Background Dietary Mg intake is associated with a decreased risk of developing heart failure, whereas low circulating Mg level is associated with increased cardiovascular mortality. We investigated whether Mg deficiency...