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Gyanu Parajuli

Explore the profile of Gyanu Parajuli including associated specialties, affiliations and a list of published articles. Areas
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Articles 4
Citations 125
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Recent Articles
1.
Parajuli G, Tekguc M, Wing J, Hashimoto A, Okuzaki D, Hirata T, et al.
Cancer Immunol Res . 2021 May; 9(8):862-876. PMID: 34006522
The acquisition of mesenchymal traits leads to immune evasion in various cancers, but the underlying molecular mechanisms remain unclear. In this study, we found that the expression levels of AT-rich...
2.
Metwally H, Tanaka T, Li S, Parajuli G, Kang S, Hanieh H, et al.
Sci Signal . 2020 Mar; 13(624). PMID: 32209697
The lipopolysaccharide (LPS)-induced endocytosis of Toll-like receptor 4 (TLR4) is an essential step in the production of interferon-β (IFN-β), which activates the transcription of antiviral response genes by STAT1 phosphorylated...
3.
Hashimoto S, Furukawa S, Hashimoto A, Tsutaho A, Fukao A, Sakamura Y, et al.
Proc Natl Acad Sci U S A . 2019 Aug; 116(35):17450-17459. PMID: 31399545
Although and mutations are major drivers of pancreatic ductal adenocarcinoma (PDAC), the incurable nature of this cancer still remains largely elusive. ARF6 and its effector AMAP1 are often overexpressed in...
4.
Chalise J, Hashimoto S, Parajuli G, Kang S, Singh S, Gemechu Y, et al.
Proc Natl Acad Sci U S A . 2019 Jul; 116(30):15128-15133. PMID: 31289228
Immune cells infiltrate adipose tissues and provide a framework to regulate energy homeostasis. However, the precise underlying mechanisms and signaling by which the immune system regulates energy homeostasis in metabolic...