Guy L Reed
Overview
Explore the profile of Guy L Reed including associated specialties, affiliations and a list of published articles.
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Articles
73
Citations
1191
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Recent Articles
1.
Gladysheva I, Sullivan R, Saleem S, Castellino F, Ploplis V, Reed G
bioRxiv
. 2024 Sep;
PMID: 39314400
Symptomatic heart failure (sHF) with cardiac dysfunction, edema, and mortality are driven by overactivation of the renin-angiotensin-aldosterone system (RAAS). Renin is widely recognized as a key initiator of RAAS function,...
2.
Wang D, Saleem S, Sullivan R, Zhao T, Reed G
Int J Mol Sci
. 2024 Sep;
25(17).
PMID: 39273389
Matrix metalloproteinases (MMPs) such as MMP-9, 3, and 2 degrade the cellular matrix and are believed to play a crucial role in ischemic stroke. We examined how the duration of...
3.
Singh S, Kumar P, Padwad Y, Jaffer F, Reed G
Circulation
. 2024 Sep;
150(11):884-898.
PMID: 39250537
Venous thrombosis and pulmonary embolism (venous thromboembolism) are important causes of morbidity and mortality worldwide. In patients with venous thromboembolism, thrombi obstruct blood vessels and resist physiological dissolution (fibrinolysis), which...
4.
Gladysheva I, Wang D, Reed G
N Engl J Med
. 2024 Apr;
390(16):1538-1539.
PMID: 38657260
No abstract available.
5.
Gladysheva I, Sullivan R, Reed G
Front Cardiovasc Med
. 2023 Jun;
10:1120487.
PMID: 37388639
No abstract available.
6.
Sullivan R, McCune M, Hernandez M, Reed G, Gladysheva I
Biomedicines
. 2022 Aug;
10(8).
PMID: 36009562
In heart failure with reduced ejection fraction (HFrEF), cardiogenic edema develops from impaired cardiac function, pathological remodeling, chronic inflammation, endothelial dysfunction, neurohormonal activation, and altered nitric oxide-related pathways. Pre-clinical HFrEF...
7.
Gladysheva I, Sullivan R, Ramanathan K, Reed G
Biomedicines
. 2022 Aug;
10(8).
PMID: 36009420
Symptomatic heart failure with reduced ejection fraction (HFrEF) is characterized by edema and chronic pathological activation of the classical renin-angiotensin-aldosterone system (RAAS). The soluble (pro)renin receptor (s(P)RR) is released into...
8.
Hernandez M, Sullivan R, McCune M, Reed G, Gladysheva I
Diagnostics (Basel)
. 2022 Apr;
12(4).
PMID: 35454037
Pathological sodium-water retention or edema/congestion is a primary cause of heart failure (HF) decompensation, clinical symptoms, hospitalization, reduced quality of life, and premature mortality. Sodium-glucose cotransporter-2 inhibitors (SGLT-2i) based therapies...
9.
Gladysheva I, Sullivan R, Reed G
JACC Heart Fail
. 2021 Apr;
9(5):406.
PMID: 33926738
No abstract available.
10.
Tripathi R, Sullivan R, Fan T, Mehta R, Gladysheva I, Reed G
Int J Mol Sci
. 2021 Apr;
22(8).
PMID: 33919841
Sodium restriction is often recommended in heart failure (HF) to block symptomatic edema, despite limited evidence for benefit. However, a low-sodium diet (LSD) activates the classical renin-angiotensin-aldosterone system (RAAS), which...