Gurumoorthy Krishnamoorthy
Overview
Explore the profile of Gurumoorthy Krishnamoorthy including associated specialties, affiliations and a list of published articles.
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35
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2815
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Recent Articles
11.
Mues M, Krishnamoorthy G
Eur J Immunol
. 2018 Dec;
49(3):500-503.
PMID: 30578685
B mice express a red fluorescent protein together with the diphtheria toxin receptor selectively in B cells. B cells can be effectively visualized by red fluorescence and can be efficiently...
12.
Janakiraman M, Krishnamoorthy G
Front Immunol
. 2018 Sep;
9:2067.
PMID: 30254641
Commensal gut microbiota exerts multifarious effects on intestinal and extra-intestinal immune homeostasis. A disruption in the microbial composition of the gut has been associated with many neurological disorders with inflammatory...
13.
Spadaro M, Winklmeier S, Beltran E, Macrini C, Hoftberger R, Schuh E, et al.
Ann Neurol
. 2018 Jul;
84(2):315-328.
PMID: 30014603
Objective: Autoantibodies against myelin oligodendrocyte glycoprotein (MOG) occur in a proportion of patients with inflammatory demyelinating diseases of the central nervous system (CNS). We analyzed their pathogenic activity by affinity-purifying...
14.
Berer K, Martinez I, Walker A, Kunkel B, Schmitt-Kopplin P, Walter J, et al.
Sci Rep
. 2018 Jul;
8(1):10431.
PMID: 29993025
The autoimmune neurological disease, Multiple Sclerosis (MS), have increased at alarming rates in the Western society over the last few decades. While there are numerous efforts to develop novel treatment...
15.
Berer K, Gerdes L, Cekanaviciute E, Jia X, Xiao L, Xia Z, et al.
Proc Natl Acad Sci U S A
. 2017 Sep;
114(40):10719-10724.
PMID: 28893994
There is emerging evidence that the commensal microbiota has a role in the pathogenesis of multiple sclerosis (MS), a putative autoimmune disease of the CNS. Here, we compared the gut...
16.
Rumble J, Huber A, Krishnamoorthy G, Srinivasan A, Giles D, Zhang X, et al.
J Exp Med
. 2015 Jan;
212(1):23-35.
PMID: 25559893
A major function of T helper (Th) 17 cells is to induce the production of factors that activate and mobilize neutrophils. Although Th17 cells have been implicated in the pathogenesis...
17.
Koutrolos M, Berer K, Kawakami N, Wekerle H, Krishnamoorthy G
Acta Neuropathol Commun
. 2014 Dec;
2:163.
PMID: 25476447
Regulatory T cells are crucial in controlling various functions of effector T cells during experimental autoimmune encephalomyelitis. While regulatory T cells are reported to exert their immunomodulatory effects in the...
18.
Ben-Nun A, Kaushansky N, Kawakami N, Krishnamoorthy G, Berer K, Liblau R, et al.
J Autoimmun
. 2014 Sep;
54:33-50.
PMID: 25175979
Multiple sclerosis (MS), a demyelinating disease of the central nervous system (CNS), presents as a complex disease with variable clinical and pathological manifestations, involving different pathogenic pathways. Animal models, particularly...
19.
Eberle M, Ebel P, Wegner M, Mannich J, Tafferner N, Ferreiros N, et al.
Biochem Pharmacol
. 2014 Sep;
92(2):326-35.
PMID: 25173988
Ceramides (Cer) are mediators of inflammatory processes. In a chronic experimental autoimmune encephalomyelitis (EAE) model of multiple sclerosis (MS), we observed a significant elevation of C16-Cer and its synthesizing enzyme,...
20.
Berer K, Krishnamoorthy G
FEBS Lett
. 2014 Apr;
588(22):4207-13.
PMID: 24746689
Not much is known about the initial events leading to the development of the central nervous system (CNS)-specific autoimmune disorder Multiple Sclerosis (MS). Environmental factors are suspected to trigger the...