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Gunnar T Dolphin

Explore the profile of Gunnar T Dolphin including associated specialties, affiliations and a list of published articles. Areas
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Articles 13
Citations 50
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Recent Articles
1.
Dolphin G, Renaudet O, Ouberai M, Dumy P, Garcia J, Reymond J
Chembiochem . 2009 May; 10(8):1325-9. PMID: 19415707
See you later amyloid beta: A screen of a small library of oxime oligomers with an HTS fluorescence assay for amyloid fibril inhibition and subsequent investigation by atomic force microscopy...
2.
Dolphin G, Chierici S, Ouberai M, Dumy P, Garcia J
Chembiochem . 2008 Mar; 9(6):952-63. PMID: 18330854
Amyloid formation and accumulation of the amyloid beta-peptide (Abeta) in the brain is associated with Alzheimer's disease (AD) pathogenesis. Therefore, among the therapeutic approaches in development to fight the disease,...
3.
Boturyn D, Defrancq E, Dolphin G, Garcia J, Labbe P, Renaudet O, et al.
J Pept Sci . 2007 Nov; 14(2):224-40. PMID: 18027902
Biologically programmed molecular recognition provides the basis of all natural systems and supplies evolution-optimized functional materials from self-assembly of a limited number of molecular building blocks. Biomolecules such as peptides,...
4.
Dolphin G, Ouberai M, Dumy P, Garcia J
ChemMedChem . 2007 Sep; 2(11):1613-23. PMID: 17876751
Amyloid beta peptide (Abeta) fibril formation is widely believed to be the causative event of Alzheimer's disease pathogenesis. Therapeutic approaches are therefore in development that target various sites in the...
5.
Singh Y, Dolphin G, Razkin J, Dumy P
Chembiochem . 2006 Aug; 7(9):1298-314. PMID: 16892470
The creation of molecular systems that can mimic some of the properties of natural macromolecules is one of the major endeavors in contemporary protein chemistry. However, the construction of artificial...
6.
Dolphin G
J Am Chem Soc . 2006 Jun; 128(22):7287-90. PMID: 16734482
The ultimate goals of de novo protein design are the construction of novel tertiary structures and functions. Here is presented the design and synthesis of a uniquely branched three-helix bundle...
7.
Dolphin G, Dumy P, Garcia J
Angew Chem Int Ed Engl . 2006 Mar; 45(17):2699-702. PMID: 16555351
No abstract available.
8.
Andersson T, Lundquist M, Dolphin G, Enander K, Jonsson B, Nilsson J, et al.
Chem Biol . 2005 Nov; 12(11):1245-52. PMID: 16298304
Several receptors for human carbonic anhydrase II (HCAII) have been prepared by covalently attaching benzenesulfonamide carboxylates via aliphatic aminocarboxylic acid spacers of variable length to the side chain of a...
9.
Dolphin G
Chemistry . 2005 Nov; 12(5):1436-47. PMID: 16283689
The design and total chemical synthesis of a monomeric native-like four-helix bundle protein is presented. The designed protein, GTD-Lig, consists of 90 amino acids and is based on the dimeric...
10.
Enander K, Dolphin G, Liedberg B, Lundstrom I, Baltzer L
Chemistry . 2004 May; 10(10):2375-85. PMID: 15146511
A molecular platform for protein detection and quantification is reported in which recognition has been integrated with direct monitoring of target-protein binding. The platform is based on a versatile 42-residue...