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Gunn-Guang Liou

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Articles 32
Citations 615
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Recent Articles
1.
Tsai M, Liou G, Liao J, Lai P, Yang D, Wu S, et al.
Antioxidants (Basel) . 2024 Jul; 13(7). PMID: 39061900
N-acetyl cysteine (NAC) is a versatile drug used in various conditions, but the limitations and toxicities are not clear. The acute toxicity and toxicological mechanisms of an intraperitoneal injection of...
2.
Dai Y, Yeh S, Cheng Y, Huang W, Liou G, Yang T, et al.
J Virol . 2024 Jan; 98(2):e0189923. PMID: 38294245
After Epstein-Barr virus (EBV) genome replication and encapsidation in the nucleus, nucleocapsids are translocated into the cytoplasm for subsequent tegumentation and maturation. The EBV BGLF4 kinase, which induces partial disassembly...
3.
Wang Y, Huang C, Liou G, Hsueh H, Liang C, Tseng H, et al.
Protein Sci . 2023 Feb; 32(4):e4610. PMID: 36851846
Transthyretin (TTR)-related amyloidosis (ATTR) is a syndrome of diseases characterized by the extracellular deposition of fibrillar materials containing TTR variants. Ala97Ser (A97S) is the major mutation reported in Taiwanese ATTR...
4.
Wong T, Liou G, Kan M
Vaccines (Basel) . 2023 Feb; 11(2). PMID: 36851303
A thermally stable vaccine platform is considered the missing piece of vaccine technology. In this article, we reported the creation of a novel protein nanoparticle and assessed its ability to...
5.
Liou G, Chao Kaberdina A, Wang W, Kaberdin V, Lin-Chao S
Int J Mol Sci . 2022 Mar; 23(5). PMID: 35269716
Adaptive mechanisms that facilitate intestinal colonization by the human microbiota, including , may be better understood by analyzing the physiology and gene expression of bacteria in low-oxygen environments. We used...
6.
Chi Y, Wang W, Hung M, Liou G, Wang J, Chao P
Epigenetics Chromatin . 2022 Jan; 15(1):1. PMID: 34983624
The cause of nuclear shape abnormalities which are often seen in pre-neoplastic and malignant tissues is not clear. In this study we report that deformation of the nucleus can be...
7.
Liou G, Hsieh C, Lee Y, Li P, Tsai M, Li C, et al.
Antioxidants (Basel) . 2021 Apr; 10(3). PMID: 33809388
Acetaminophen (APAP) overdose induces acute liver damage and even death. The standard therapeutic dose of N-acetyl cysteine (NAC) cannot be applied to every patient, especially those with high-dose APAP poisoning....
8.
Lin S, Hsieh T, Liou G, Li T, Lin H, Chang C, et al.
Cell Rep . 2020 Oct; 33(4):108310. PMID: 33113375
Neuromuscular junctions (NMJs) govern efficient neuronal communication with muscle cells, relying on proper architecture of specialized postsynaptic compartments. However, the intrinsic mechanism in muscle cells contributing to NMJ development remains...
9.
Bhupana J, Huang B, Liou G, Calkins M, Lin-Chao S
FASEB Bioadv . 2020 Mar; 2(3):166-181. PMID: 32161906
Dynamic fission and fusion events regulate mitochondrial shape, distribution, and rejuvenation, and proper control of these processes is essential for neuronal homeostasis. Here, we report that Gas7, a known cytoskeleton...
10.
Hsu C, Liou G, Jiang Y
J Invest Dermatol . 2019 Aug; 140(2):404-414.e13. PMID: 31437444
Skin depigmentation diseases, such as vitiligo, are pigmentation disorders that often destroy melanocytes. However, their pathological mechanisms remain unclear, and therefore, promising treatments or prevention has been lacking. Here, we...