Guixiong Fan
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Explore the profile of Guixiong Fan including associated specialties, affiliations and a list of published articles.
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24
Citations
377
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Recent Articles
1.
Jia Y, Ye Z, Wang X, Deng Y, Wang C, Zhang Z, et al.
Acta Biochim Biophys Sin (Shanghai)
. 2025 Mar;
PMID: 40065720
Ferroptosis is a type of programmed death characterized by iron-dependent lipid peroxidation, and targeting ferroptosis has been shown to efficiently kill highly aggressive cancer cells. Previously, we confirmed that nuclear...
2.
Li B, Xing F, Wang J, Wang X, Zhou C, Fan G, et al.
Cancer Lett
. 2024 Aug;
602:217197.
PMID: 39216548
Pancreatic ductal adenocarcinoma (PDAC) is highly malignant and has a poor prognosis, without effective therapeutic targets in common gene mutations. Gemcitabine, a first-line chemotherapeutic for PDAC, confers <10 % 5-year...
3.
Xu J, Lou X, Wang F, Zhang W, Xu X, Ye Z, et al.
Adv Sci (Weinh)
. 2024 Jul;
11(35):e2308417.
PMID: 39041891
O6-methylguanine DNA methyltransferase (MGMT) removes alkyl adducts from the guanine O6 position (O-MG) and repairs DNA damage. High MGMT expression results in poor response to temozolomide (TMZ). However, the biological...
4.
Wang T, Hu Q, Li B, Fan G, Jing D, Xu J, et al.
Cell Prolif
. 2024 Jun;
57(11):e13694.
PMID: 38938061
Pancreatic cancer cells have a much higher metabolic demand than that of normal cells. However, the abundant interstitium and lack of blood supply determine the lack of nutrients in the...
5.
Ye Z, Li Q, Hu Y, Hu H, Xu J, Guo M, et al.
Cancer Lett
. 2024 Mar;
588:216769.
PMID: 38438098
Cancer-associated fibroblasts (CAFs) play an important role in a variety of cancers. However, the role of tumor stroma in nonfunctional pancreatic neuroendocrine tumors (NF-PanNETs) is often neglected. Profiling the heterogeneity...
6.
Wang X, Jia Y, Xu X, Hu Y, Fan G, Jing D, et al.
Cancer Med
. 2023 Aug;
12(17):18425-18439.
PMID: 37553876
Background: Nuclear receptor coactivator 6 (NCoA6) is overexpressed in various cancers and considered a multifunctional coactivator of various transcription factors and nuclear receptors. However, the role of NCoA6 in pancreatic...
7.
Xu J, Ye Z, Zhuo Q, Gao H, Qin Y, Lou X, et al.
Cancer Res
. 2023 Mar;
83(13):2226-2247.
PMID: 36939378
Significance: Identification of neddylation and ubiquitination pathways that regulate MEN1 protein stability provides an opportunity for therapeutic interventions for treating patients with pancreatic neuroendocrine tumors.
8.
Lu Z, Hu Q, Qin Y, Yang H, Xiao B, Chen W, et al.
Cancer Cell Int
. 2023 Mar;
23(1):50.
PMID: 36934248
Background: As an oncogene, SETD8 can promote tumour growth and tumour cell proliferation. This study aims to reveal the relationship between SETD8 and ferroptosis in pancreatic cancer and its role...
9.
Ye Z, Chen H, Ji S, Hu Y, Lou X, Zhang W, et al.
Acta Biochim Biophys Sin (Shanghai)
. 2023 Jan;
54(11):1599-1609.
PMID: 36604142
Pancreatic neuroendocrine tumor (pNET) is the second most common malignant tumors of the pancreas. Multiple endocrine neoplasia 1 ( ) is the most frequently mutated gene in pNETs and MEN1-encoded...
10.
Zhang Z, Wang F, Li Z, Ye Z, Zhuo Q, Xu W, et al.
BMC Surg
. 2022 May;
22(1):160.
PMID: 35538535
Background: Although some factors that predict the prognosis in pancreatic neuroendocrine tumor (pNET) have been confirmed, the predictive value of lymph node metastasis (LNM) in the prognosis of pNETs remains...