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Guimei Ji

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Articles 7
Citations 78
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Recent Articles
1.
Qin W, Duan Y, Hu Z, Hou Y, Wen T, Ouyang Y, et al.
J Exp Med . 2025 Mar; 222(5). PMID: 40048154
Hypoxia induces immunosuppressive phenotypes in tumor cells even in the presence of cytosolic DNA accumulation. The mechanisms by which tumor cells suppress hypoxia-induced cGAS-STING activation for immune evasion remain largely...
2.
Wang L, Shi R, Wang S, Duan Y, Wang Z, Zheng P, et al.
Nat Chem Biol . 2025 Jan; PMID: 39881212
As an enzyme with a critical role in de novo purine synthesis, adenylosuccinate lyase (ADSL) expression is upregulated in various malignancies. However, whether ADSL possesses noncanonical functions that contribute to...
3.
Wang Z, Yan M, Ye L, Zhou Q, Duan Y, Jiang H, et al.
EMBO J . 2024 Feb; 43(6):931-955. PMID: 38360997
The Von Hippel-Lindau (VHL) protein, which is frequently mutated in clear-cell renal cell carcinoma (ccRCC), is a master regulator of hypoxia-inducible factor (HIF) that is involved in oxidative stresses. However,...
4.
Wu K, Yan M, Liu T, Wang Z, Duan Y, Xia Y, et al.
Nat Cell Biol . 2023 May; 25(5):714-725. PMID: 37156912
Activation of receptor protein kinases is prevalent in various cancers with unknown impact on ferroptosis. Here we demonstrated that AKT activated by insulin-like growth factor 1 receptor signalling phosphorylates creatine...
5.
Liu T, Wang Z, Ye L, Duan Y, Jiang H, He H, et al.
Nat Cell Biol . 2023 Jan; 25(2):273-284. PMID: 36646788
Impairment of the circadian clock is linked to cancer development. However, whether the circadian clock is modulated by oncogenic receptor tyrosine kinases remains unclear. Here we demonstrated that receptor tyrosine...
6.
Wang Z, Li M, Jiang H, Luo S, Shao F, Xia Y, et al.
Nat Cell Biol . 2022 Oct; 24(11):1655-1665. PMID: 36266488
Tumour cells exhibit greater metabolic plasticity than normal cells and possess selective advantages for survival and proliferation with unclearly defined mechanisms. Here we demonstrate that glucose deprivation in normal hepatocytes...
7.
Ma T, Zhang Y, Meng J, Yang F, Zhang H, Li B, et al.
Br J Anaesth . 2022 Mar; 128(5):e322-e324. PMID: 35256152
No abstract available.
8.
Li X, Niu Z, Sun C, Zhuo S, Yang H, Yang X, et al.
Cell Death Dis . 2022 Feb; 13(2):149. PMID: 35165289
The tumor suppressor P53 plays critical role in preventing cancer. P53 is rarely mutated and remains functional in luminal-type breast cancer(1). According to current knowledge, wild-type P53 function is tightly...
9.
Lu K, Zhao L, Zhang Y, Yang F, Zhang H, Wang J, et al.
Sci Rep . 2022 Jan; 12(1):1378. PMID: 35082359
Bupivacaine, a local anaesthetic, is widely applied in the epidural or subarachnoid space to clinically manage acute and chronic pain. However, the underlying mechanisms are complex and unclear. Glycine transporter...