Guillermo M Alexander
Overview
Explore the profile of Guillermo M Alexander including associated specialties, affiliations and a list of published articles.
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Articles
32
Citations
1038
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Recent Articles
1.
Alexander G, Heiman-Patterson T, Bearoff F, Sher R, Hennessy L, Terek S, et al.
PLoS One
. 2022 Sep;
17(9):e0274615.
PMID: 36107978
Amyotrophic lateral sclerosis (ALS) is the most common degenerative motor neuron disorder. Although most cases of ALS are sporadic, 5-10% of cases are familial, with mutations associated with over 40...
2.
Pande R, Parikh A, Shenoda B, Ramanathan S, Alexander G, Schwartzman R, et al.
Biomed Pharmacother
. 2021 Jun;
140:111788.
PMID: 34062414
Complex regional pain syndrome (CRPS) is a chronic pain condition characterized by inflammation and debilitating pain. CRPS patients with pain refractory to more conventional analgesics can be treated with subanesthetic...
3.
Shenoda B, Ramanathan S, Gupta R, Tian Y, Jean-Toussaint R, Alexander G, et al.
Cell Mol Life Sci
. 2020 Mar;
78(1):299-316.
PMID: 32193609
Biological sex influences inflammatory response, as there is a greater incidence of acute inflammation in men and chronic inflammation in women. Here, we report that acute inflammation is attenuated by...
4.
Ramanathan S, Shenoda B, Lin Z, Alexander G, Huppert A, Sacan A, et al.
J Extracell Vesicles
. 2019 Sep;
8(1):1650595.
PMID: 31489147
Extracellular RNA in circulation mediates intercellular communication in normal and pathological processes. One mode of circulating miRNA transport in bodily fluids is within 30-150 nm small extracellular vesicles (sEVs) or...
5.
Ramanathan S, Douglas S, Alexander G, Shenoda B, Barrett J, Aradillas E, et al.
J Transl Med
. 2019 Mar;
17(1):81.
PMID: 30871575
Background: Therapeutic plasma exchange (PE) or plasmapheresis is an extracorporeal procedure employed to treat immunological disorders. Exosomes, nanosized vesicles of endosomal origin, mediate intercellular communication by transferring cargo proteins and...
6.
Qiang L, Piermarini E, Muralidharan H, Yu W, Leo L, Hennessy L, et al.
Hum Mol Genet
. 2018 Dec;
28(7):1136-1152.
PMID: 30520996
Mutations of the SPAST gene, which encodes the microtubule-severing protein spastin, are the most common cause of hereditary spastic paraplegia (HSP). Haploinsufficiency is the prevalent opinion as to the mechanism...
7.
Shenoda B, Tian Y, Alexander G, Aradillas-Lopez E, Schwartzman R, Ajit S
J Pain Res
. 2018 May;
11:935-945.
PMID: 29773953
Background: Evidence is overwhelming for sex differences in pain, with women representing the majority of the chronic pain patient population. There is a need to explore novel avenues to elucidate...
8.
Janicki P, Alexander G, Eckert J, Postula M, Schwartzman R
Pain Med
. 2016 Dec;
17(12):2344-2352.
PMID: 28025368
Objective: The objective of this study was to use a genome-wide association (GWAS) approach and pooled DNA strategy to search for new genomic loci associated with complex regional pain syndrome...
9.
McDonald M, Ramanathan S, Touati A, Zhou Y, Thanawala R, Alexander G, et al.
Sci Rep
. 2016 Aug;
6:30976.
PMID: 27498764
Circulating microRNAs are beneficial biomarkers because of their stability and dysregulation in diseases. Here we sought to determine the role of miR-939, a miRNA downregulated in patients with complex regional...
10.
Shenoda B, Alexander G, Ajit S
J Transl Med
. 2016 Mar;
14:64.
PMID: 26940669
Background: Ketamine provides relief for a subset of patients with complex regional pain syndrome (CRPS). The poor responders had a lower body mass index (BMI) relative to responders. Regulation of...