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Guillaume O Adelmant

Explore the profile of Guillaume O Adelmant including associated specialties, affiliations and a list of published articles. Areas
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Articles 6
Citations 322
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Recent Articles
1.
Pan L, Lemieux M, Thomas T, Rogers J, Lipper C, Lee W, et al.
Elife . 2020 Sep; 9. PMID: 32936072
Notch signaling regulates squamous cell proliferation and differentiation and is frequently disrupted in squamous cell carcinomas, in which Notch is tumor suppressive. Here, we show that conditional activation of Notch...
2.
Lee D, Goodarzi A, Adelmant G, Pan Y, Jeggo P, Marto J, et al.
EMBO J . 2012 Apr; 31(10):2403-15. PMID: 22491012
Protein phosphatase PP4C has been implicated in the DNA damage response (DDR), but its substrates in DDR remain largely unknown. We devised a novel proteomic strategy for systematic identification of...
3.
Pathania S, Nguyen J, Hill S, Scully R, Adelmant G, Marto J, et al.
Mol Cell . 2011 Oct; 44(2):235-51. PMID: 21963239
BRCA1 contributes to the response to UV irradiation. Utilizing its BRCT motifs, it is recruited during S/G2 to UV-damaged sites in a DNA replication-dependent but nucleotide excision repair (NER)-independent manner....
4.
Chen Z, Sasaki T, Tan X, Carretero J, Shimamura T, Li D, et al.
Cancer Res . 2010 Oct; 70(23):9827-36. PMID: 20952506
Genetic rearrangements of the anaplastic lymphoma kinase (ALK) kinase occur in 3% to 13% of non-small cell lung cancer patients and rarely coexist with KRASor EGFR mutations. To evaluate potential...
5.
Zhou F, Cardoza J, Ficarro S, Adelmant G, Lazaro J, Marto J
J Proteome Res . 2010 Sep; 9(12):6242-55. PMID: 20873769
Tandem affinity purification (TAP) coupled with mass spectrometry has become the technique of choice for characterization of multicomponent protein complexes. While current TAP protocols routinely provide high yield and specificity...
6.
Simarro M, Gimenez-Cassina A, Kedersha N, Lazaro J, Adelmant G, Marto J, et al.
Biochem Biophys Res Commun . 2010 Sep; 401(3):440-6. PMID: 20869947
Fas-activated serine/threonine phosphoprotein (FAST) is the founding member of the FAST kinase domain-containing protein (FASTKD) family that includes FASTKD1-5. FAST is a sensor of mitochondrial stress that modulates protein translation...