Guidalberto Manfioletti
Overview
Explore the profile of Guidalberto Manfioletti including associated specialties, affiliations and a list of published articles.
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66
Citations
1773
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Recent Articles
1.
Battista S, Fedele M, Secco L, Ingo A, Sgarra R, Manfioletti G
Int J Mol Sci
. 2024 Aug;
25(16).
PMID: 39201549
The "AT-hook" is a peculiar DNA-binding domain that interacts with DNA in the minor groove in correspondence to AT-rich sequences. This domain has been first described in the HMGA protein...
2.
Mori M, Ghirga F, Amato B, Secco L, Quaglio D, Romeo I, et al.
ACS Omega
. 2023 Sep;
8(36):32424-32431.
PMID: 37720761
HMGA proteins are intrinsically disordered (ID) chromatin architectural factors characterized by three DNA binding domains (AT-hooks) that allow them to bind into the DNA minor groove of AT-rich stretches. HMGA...
3.
Manfioletti G, Fedele M
Int J Mol Sci
. 2023 Jul;
24(14).
PMID: 37511145
Epithelial-mesenchymal transition (EMT) is a cellular process involved in many physiological and pathological conditions [...].
4.
Spolaore B, Secco L, Rocca G, Manfioletti G, Arrigoni G, Sgarra R
Expert Rev Proteomics
. 2023 May;
20(4-6):93-107.
PMID: 37219402
Introduction: Intrinsically disordered proteins (IDPs) represent a family of proteins that lack secondary or tertiary structure. IDPs are hubs in interaction networks, participate in liquid-liquid phase separation processes, and drive...
5.
Sgarra R, Battista S, Cerchia L, Manfioletti G, Fedele M
Antioxid Redox Signal
. 2023 Feb;
40(4-6):236-249.
PMID: 36851901
Metabolic end products and intermediates can exert signaling functions as chemical sources for histone posttranslational modifications, which remodel chromatin and affect gene expression. Among them, lactic acid is responsible for...
6.
Petrosino S, Pacor S, Pegoraro S, Gazziero V, Canarutto G, Piazza S, et al.
Int J Mol Sci
. 2023 Jan;
24(1).
PMID: 36614035
Breast cancer (BC) is the primary cause of cancer mortality in women and the triple-negative breast cancer (TNBC) is the most aggressive subtype characterized by poor differentiation and high proliferative...
7.
Zambelli A, Sgarra R, De Sanctis R, Agostinetto E, Santoro A, Manfioletti G
Expert Opin Ther Targets
. 2022 May;
26(6):557-573.
PMID: 35638300
Introduction: Triple-negative breast cancer (TNBC) is considered the most aggressive breast cancer subtype with the least favorable outcomes. However, recent research efforts have generated an enhanced knowledge of the biology...
8.
Manfioletti G, Fedele M
Int J Mol Sci
. 2022 May;
23(10).
PMID: 35628655
Epithelial-mesenchymal transition (EMT) is a transdifferentiation process wherein epithelial cells acquire characteristics typical of mesenchymal cells [...].
9.
Sgubin M, Pegoraro S, Pellarin I, Ros G, Sgarra R, Piazza S, et al.
Cell Death Dis
. 2022 May;
13(5):429.
PMID: 35504904
High Mobility Group A1 (HMGA1) is an architectural chromatin factor involved in the regulation of gene expression and a master regulator in Triple Negative Breast Cancer (TNBC). In TNBC, HMGA1...
10.
Fedele M, Sgarra R, Battista S, Cerchia L, Manfioletti G
Int J Mol Sci
. 2022 Jan;
23(2).
PMID: 35054987
The transition between epithelial and mesenchymal phenotype is emerging as a key determinant of tumor cell invasion and metastasis. It is a plastic process in which epithelial cells first acquire...