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» Authors » Guftar Shaikh

Guftar Shaikh

Explore the profile of Guftar Shaikh including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 16
Citations 114
Followers 0
Related Specialties
Endocrinology
Genetics
Pediatrics
Top 10 Co-Authors
Edna Roche
Rikke Beck Jensen
Hilary Hoey
Ajay Thankamony
Anders Juul
Olle Soder
Sten-A Ivarsson
Martin Zenker
Thomas Edouard
Indraneel Banerjee
Published In
J Clin Endocrinol Metab
Eur J Med Genet
Shock
Acta Paediatr
Arch Dis Child Educ Pract Ed
Affiliations
Soon will be listed here.
Recent Articles
1.
Continuous Glucose Monitoring-Derived Glycemic Phenotyping of Childhood Hypoglycemia due to Hyperinsulinism: A Year-long Prospective Nationwide Observational Study
Worth C, Auckburally S, Worthington S, Ahmad S, OShea E, Senniappan S, et al.
J Diabetes Sci Technol . 2024 Nov; :19322968241255842. PMID: 39564699
Background: The glycemic characterization of congenital hyperinsulinism (HI), a rare disease causing severe hypoglycemia in childhood, is incomplete. Continuous glucose monitoring (CGM) offers deep glycemic phenotyping to understand disease burden...
2.
ADVANCING THE UNDERSTANDING OF CLINICAL SEPSIS USING GENE EXPRESSION-DRIVEN MACHINE LEARNING TO IMPROVE PATIENT OUTCOMES
Rashid A, Al-Obeida F, Hafez W, Benakatti G, Malik R, Koutentis C, et al.
Shock . 2023 Sep; 61(1):4-18. PMID: 37752080
Sepsis remains a major challenge that necessitates improved approaches to enhance patient outcomes. This study explored the potential of machine learning (ML) techniques to bridge the gap between clinical data...
3.
A TRANSCRIPTOMIC APPRECIATION OF CHILDHOOD MENINGOCOCCAL AND POLYMICROBIAL SEPSIS FROM A PRO-INFLAMMATORY AND TRAJECTORIAL PERSPECTIVE, A ROLE FOR VASCULAR ENDOTHELIAL GROWTH FACTOR A AND B MODULATION?
Rashid A, Brusletto B, Al-Obeidat F, Toufiq M, Benakatti G, Brierley J, et al.
Shock . 2023 Aug; 60(4):503-516. PMID: 37553892
This study investigated the temporal dynamics of childhood sepsis by analyzing gene expression changes associated with proinflammatory processes. Five datasets, including four meningococcal sepsis shock (MSS) datasets (two temporal and...
4.
Response to Letter to the Editor From Arroyo et al: "Timing of Puberty, Pubertal Growth, and Adult Height in Short Children Born Small for Gestational Age Treated With Growth Hormone"
Upners E, Raket L, Petersen J, Thankamony A, Roche E, Shaikh G, et al.
J Clin Endocrinol Metab . 2023 Apr; 108(10):e1161. PMID: 37097735
No abstract available.
5.
Timing of Puberty, Pubertal Growth, and Adult Height in Short Children Born Small for Gestational Age Treated With Growth Hormone
Upners E, Raket L, Petersen J, Thankamony A, Roche E, Shaikh G, et al.
J Clin Endocrinol Metab . 2022 May; 107(8):2286-2295. PMID: 35521800
Context: Growth hormone (GH) is used to treat short children born small for gestational age (SGA); however, the effects of treatment on pubertal timing and adult height are rarely studied....
6.
Management of growth failure and other endocrine aspects in patients with Noonan syndrome across Europe: A sub-analysis of a European clinical practice survey
Edouard T, Zenker M, Ostman-Smith I, Ortega Castello E, Wolf C, Burkitt-Wright E, et al.
Eur J Med Genet . 2021 Dec; 65(1):104404. PMID: 34896604
Aim: To date, there is a lack of international guidelines regarding the management of the endocrine features of individuals with Noonan syndrome (NS). The aim was to develop a clinical...
7.
European Medical Education Initiative on Noonan syndrome: A clinical practice survey assessing the diagnosis and clinical management of individuals with Noonan syndrome across Europe
Garcia-Minaur S, Burkitt-Wright E, Verloes A, Shaikh G, Lebl J, Ostman-Smith I, et al.
Eur J Med Genet . 2021 Nov; 65(1):104371. PMID: 34757053
Introduction: Noonan syndrome (NS) is a rare genetic disorder caused by mutations in genes encoding components of the RAS/mitogen-activated protein kinase (MAPK) signalling pathway. Patients with NS exhibit certain characteristic...
8.
Management of cardiac aspects in children with Noonan syndrome - results from a European clinical practice survey among paediatric cardiologists
Wolf C, Zenker M, Burkitt-Wright E, Edouard T, Garcia-Minaur S, Lebl J, et al.
Eur J Med Genet . 2021 Nov; 65(1):104372. PMID: 34757052
Background: The majority of children with Noonan syndrome (NS) or other diseases from the RASopathy spectrum suffer from congenital heart disease. This study aims to survey cardiac care of this...
9.
Using referral rates for genetic testing to determine the incidence of a rare disease: The minimal incidence of congenital hyperinsulinism in the UK is 1 in 28,389
Yau D, Laver T, Dastamani A, Senniappan S, Houghton J, Shaikh G, et al.
PLoS One . 2020 Feb; 15(2):e0228417. PMID: 32027664
Congenital hyperinsulinism (CHI) is a significant cause of hypoglycaemia in neonates and infants with the potential for permanent neurologic injury. Accurate calculations of the incidence of rare diseases such as...
10.
Increases in Bioactive IGF do not Parallel Increases in Total IGF-I During Growth Hormone Treatment of Children Born SGA
Wegmann M, Jensen R, Thankamony A, Frystyk J, Roche E, Hoey H, et al.
J Clin Endocrinol Metab . 2019 Oct; 105(4). PMID: 31665326
Background: Some children born small for gestational age (SGA) experience supra-physiological insulin-like growth factor-I (IGF-I) concentrations during GH treatment. However, measurements of total IGF-I concentrations may not reflect the bioactive...