Guanjian Zhao
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Explore the profile of Guanjian Zhao including associated specialties, affiliations and a list of published articles.
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11
Citations
97
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Recent Articles
1.
Tang J, Yue J, Tao Y, Zhao G, Yi X, Zhang M, et al.
Transl Stroke Res
. 2024 Dec;
PMID: 39733198
Perihematomal edema (PHE) significantly aggravates secondary brain injury in patients with intracerebral hemorrhage (ICH), yet its detailed mechanisms remain elusive. Neutrophil extracellular traps (NETs) are known to exacerbate neurological deficits...
2.
Zhang Z, Ji X, Tao Y, Huang N, Wen R, Tang J, et al.
Trials
. 2024 Jan;
25(1):33.
PMID: 38195481
Background: Patients undergoing carotid endarterectomy (CEA) have a high restenosis rate, which increases the risk of stroke, and there is still a lack of effective treatment for restenosis. The cause...
3.
Sun M, Xie H, Zhang W, Li X, Jiang Z, Liang Y, et al.
Adv Sci (Weinh)
. 2023 Dec;
11(6):e2306190.
PMID: 38049204
Radiotherapy (RT) resistance is an enormous challenge in glioblastoma multiforme (GBM) treatment, which is largely associated with DNA repair, poor distribution of reactive radicals in tumors, and limited delivery of...
4.
Luo H, Zhang H, Mao J, Cao H, Tao Y, Zhao G, et al.
Cell Death Dis
. 2023 Apr;
14(4):235.
PMID: 37012233
Exosomes, the cell-derived small extracellular vehicles, play a vital role in intracellular communication by reciprocally transporting DNA, RNA, bioactive protein, chains of glucose, and metabolites. With great potential to be...
5.
Sun M, Huang N, Tao Y, Wen R, Zhao G, Zhang X, et al.
Trials
. 2022 Mar;
23(1):234.
PMID: 35346332
Background: Temozolomide is applied as the standard chemotherapy agent in patients with glioblastoma (GBM) after surgery. However, the benefit of this treatment for patients is limited by the invasive growth...
6.
Zhang X, Wang Y, Tan J, Zhao G, Ma M, Chen J, et al.
BMC Neurol
. 2022 Feb;
22(1):52.
PMID: 35151259
Background: Transsphenoidal surgery is the preferred first-line therapy for most pituitary adenoma(PA), and the conventional strategy of treatment is intracapsular resection(IR). The protocol of extracapsular resection(ER), which considers the pseudocapsule...
7.
Cheng Y, Chen J, Zhao G, Xie Z, Huang N, Yang Q, et al.
Front Neurol
. 2021 Jan;
11:561781.
PMID: 33510703
Spontaneous intracerebral hemorrhage (ICH) is a devastating disease with higher mortality and disability rates; however, ideal surgical management is still to be determined for critical ICH. The purpose of this...
8.
Huang N, Zhao G, Yang Q, Tan J, Tan Y, Zhang J, et al.
Aging (Albany NY)
. 2020 Nov;
12(22):23114-23128.
PMID: 33203795
Pituitary adenoma (PA) is mostly benign intracranial tumor, but it also displays invasive growth characteristics and provokes challenging clinical conditions. S100A9 protein enhances tumor progression. In this study, we firstly...
9.
Zhang P, Tang M, Huang Q, Zhao G, Huang N, Zhang X, et al.
Biochem Biophys Res Commun
. 2019 Jan;
509(2):549-556.
PMID: 30600180
Mesoporous silica nanoparticles (MSNPs) of a small diameter were loaded with the anticancer drug temozolomide (TMZ), coated with polydopamine (PDA), and conjugated with Asn-Gly-Arg (NGR) for use in the treatment...
10.
Zhao G, Huang Q, Wang F, Zhang X, Hu J, Tan Y, et al.
Cancer Lett
. 2018 Jan;
418:147-158.
PMID: 29339208
Our previous studies have demonstrated that focused ultrasound (FUS) combined with DNA-loaded microbubbles (MBs) can induce noninvasive, reversible, local disruption of the blood brain barrier (BBB) and enable targeted exogenous...