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Guangyu Wei

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Articles 14
Citations 113
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Recent Articles
1.
Wang X, Wei G, Ding Y, Gui X, Tong H, Xu X, et al.
Blood . 2022 Jun; 140(9):1038-1051. PMID: 35767715
Protein tyrosine phosphatase nonreceptor type 22 (PTPN22) is a protein tyrosine phosphatase that negatively regulates T-cell signaling. However, whether it is expressed and functions in platelets remains unknown. Here we...
2.
Wang X, Lu J, Wei G, Tong H, Zhou J, Ding Y, et al.
Ann Hematol . 2020 Jul; 99(10):2315-2322. PMID: 32728937
Immune thrombocytopenia (ITP) is an autoimmune disease characterized by lower platelet count resulting from immune cells-mediated platelet clearance. Tacrolimus is an immunosuppressive agent which selectively inhibits T cell activation. Whether...
3.
Wang X, Zhang S, Ding Y, Tong H, Xu X, Wei G, et al.
Redox Biol . 2020 May; 34:101569. PMID: 32422541
NADPH oxidase-derived reactive oxygen species (ROS) regulates platelet function and thrombosis. It remains controversial regarding NOX2's role in platelet function. As a regulatory subunit for NOX2, whether p47phox regulates platelet...
4.
Wei G, Xu X, Tong H, Wang X, Chen Y, Ding Y, et al.
Aging (Albany NY) . 2020 May; 12(9):8151-8166. PMID: 32352928
Salidroside is the main bioactive component in and possesses multiple biological and pharmacological properties. However, whether salidroside affects platelet function remains unclear. Our study aims to investigate salidroside's effect on...
5.
Liu W, Wu P, Wei G, Lu Q, Yu M, Wang Q, et al.
Appl Opt . 2019 Dec; 58(36):9734-9739. PMID: 31873613
The separation of misalignment aberrations is a crucial step in interferometric testing for the acquisition of the real surface. In this paper, a Fizeau interference system and a conical mirror...
6.
Xu M, Wang X, Xu X, Wei G, Lu W, Luo Q, et al.
Thromb Res . 2019 Nov; 183:69-75. PMID: 31670229
Immune thrombocytopenia (ITP) is a heterogeneous autoimmune disorder characterized by immune-mediated platelet destruction, leading to lower platelet count. Thalidomide is considered as a novel immunomodulatory drug for treating several autoimmune...
7.
Luo Q, Wei G, Wang X, Xu X, Ju W, Li Z, et al.
Thromb Haemost . 2019 Aug; 119(10):1655-1664. PMID: 31370073
All-trans retinoic acid (ATRA) is widely used for induction of complete remission in patients with acute promyelocytic leukemia (APL). ATRA also regulates protein kinase C (PKC) activity. Therapeutic use of...
8.
Lu J, Hu P, Wei G, Luo Q, Qiao J, Geng D
J Int Med Res . 2019 Feb; 47(4):1731-1739. PMID: 30799665
Objective: To investigate the role of alteplase, a widely-used thrombolytic drug, in platelet function. Methods: Human platelets were incubated with different concentrations of alteplase followed by analysis of platelet aggregation...
9.
Wei G, Luo Q, Wang X, Wu X, Xu M, Ding N, et al.
Int Immunopharmacol . 2018 Nov; 66:91-98. PMID: 30445311
Immune thrombocytopenia (ITP) is a heterogeneous autoimmune disease, characterized by accelerated platelet destruction/clearance or decreased platelet production. ADAM17-mediated platelet receptor GPIbα extracellular domain shedding has been shown to be involved...
10.
Luo Q, Wei G, Wu X, Tang K, Xu M, Wu Y, et al.
J Transl Med . 2018 Nov; 16(1):311. PMID: 30442147
Background: Platycodin D (PD) is one of the major bioactive components of the roots of Platycodon grandiflorum and possesses multiple biological and pharmacological properties, such as antiviral, anti-inflammatory, and anti-cancer...