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Guang-Hui Jin

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Articles 26
Citations 391
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Recent Articles
1.
Yuan J, Gu G, Jin B, Han Q, Li B, Zhang L, et al.
Cell Death Dis . 2025 Mar; 16(1):163. PMID: 40057469
Lysosome-mediated autophagy (including mitophagy) is crucial for cell survival and homeostasis. Although the mechanisms of lysosome activation during stress are well recognized, the epigenetic regulation of lysosomal gene expression remains...
2.
Liu A, Sun X, Liu D, Xu F, Feng S, Zhang S, et al.
Heliyon . 2023 May; 9(4):e15345. PMID: 37123979
Background: Hypertrophic scar (HS) and keloid (KD) are common dermal fibroproliferative growth caused by pathological wound healing. HS's prevalence is currently undetermined in China. Though it primarily occurs in dark-skinned...
3.
Zhu L, Yuan J, Zhang L, He C, Lin X, Xu B, et al.
Cancer Res . 2022 Sep; 82(22):4153-4163. PMID: 36098964
Significance: Activation of mutant Kras is dependent on MLL-mediated epigenetic regulation of Rasgrf1, conferring sensitivity to small-molecule inhibition of MLL in Kras-driven lung cancer.
4.
Zhang C, Xiang L, Chen X, Wang X, Wu K, Zhang B, et al.
Invest Ophthalmol Vis Sci . 2020 Mar; 61(3):12. PMID: 32176259
Purpose: The microRNA cluster miR-183C, which includes miR-183 and two other genes, is critical for multiple sensory systems. In mouse retina, removal of this cluster results in photoreceptor defects in...
5.
Qiu H, Jin B, Wang Z, Xu B, Zheng Q, Zhang L, et al.
Nat Commun . 2020 Feb; 11(1):1009. PMID: 32081882
The MEN1 gene, a tumor suppressor gene that encodes the protein menin, is mutated at high frequencies in neuroendocrine (NE) tumors; however, the biological importance of this gene in NE-type...
6.
Wang Z, Hong X, Zhu L, Zhang L, Qiu H, Zhang Y, et al.
Cancer Gene Ther . 2019 Aug; 27(7-8):539-547. PMID: 31383953
Several brain tumors is closely related to the disorder of chromatin histone modification, whereas the epigenetic mechanisms of the incidence of highly malignant adult glioma is not yet deeply studied....
7.
Cai X, Wu K, Zhang X, Lv J, Jin G, Xiang L, et al.
Clin Genet . 2019 Apr; 96(1):61-71. PMID: 30945270
Adenosine diphosphate (ADP)-ribosylation factor-like 2 (ARL2) protein participates in a broad range of cellular processes and acts as a mediator for mutant ARL2BP in cilium-associated retinitis pigmentosa and for mutant...
8.
Wu K, Chen X, Jin G, Wang X, Yang D, Li Y, et al.
Invest Ophthalmol Vis Sci . 2019 Mar; 60(4):1265-1274. PMID: 30924851
Purpose: MicroRNA-182 (miR-182) is abundantly expressed in mammalian retinas; however, the association between miR-182 and retinal function remains unclear. In this study, we explored whether miR-182 contributes to functional decline...
9.
Zheng Q, Xu B, Wang H, Ding L, Liu J, Zhu L, et al.
Biochim Biophys Acta Gene Regul Mech . 2018 Feb; 1861(2):117-124. PMID: 29413895
The expression of insulin-like growth factor 2 (IGF2), a classical imprinting gene, didn't completely correlate with its imprinting profiles in hepatocellular carcinoma (HCC). The mechanistic importance of promoter activity in...
10.
Du J, Shao S, Jin G, Qian C, Xu W, Lu X
Medicine (Baltimore) . 2017 Nov; 96(44):e8489. PMID: 29095308
Because of the aging population and the shortage of standardized institutional solutions for long-term care (LTC) in China, family caregivers in Beijing are increasingly called upon to provide home care...