Guan-Cheng Li
Overview
Explore the profile of Guan-Cheng Li including associated specialties, affiliations and a list of published articles.
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Articles
54
Citations
684
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0
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Recent Articles
1.
Anchoring super-enhancer-driven oncogenic lncRNAs for anti-tumor therapy in hepatocellular carcinoma
Yuan X, Zhou N, Wang J, Yang X, Wang S, Zhang C, et al.
Mol Ther
. 2022 Dec;
31(6):1756-1774.
PMID: 36461633
Super-enhancer (SE) plays a vital role in the determination of cell identity and fate. Up-regulated expression of coding genes is frequently associated with SE. However, the transcription dysregulation driven by...
2.
Peng J, Cai D, Zeng R, Zhang C, Li G, Chen S, et al.
Adv Sci (Weinh)
. 2022 Oct;
:e2204711.
PMID: 36307901
Superenhancers drive abnormal gene expression in tumors and promote malignancy. However, the relationship between superenhancer-associated long noncoding RNA (lncRNA) and abnormal metabolism is unknown. This study identifies a novel lncRNA,...
3.
Peng L, Zhou N, Zhang C, Li G, Yuan X
Oncogene
. 2022 Apr;
41(19):2696-2705.
PMID: 35388171
Extrachromosomal circular DNA (eccDNA) elements are circular DNA molecules that are derived from but are independent of chromosomal DNA. EccDNA is emerging as a rising star because of its ubiquitous...
4.
Peng L, Yuan X, Zhang C, Peng J, Zhang Y, Pan X, et al.
J Cancer
. 2018 Jul;
9(14):2549-2558.
PMID: 30026854
Hepatocellular carcinoma (HCC) accounting for roughly 90% of all primary liver neoplasms is the sixth most frequent neoplasm and the second prominent reason of tumor fatality worldwide. As regulators of...
5.
Liu W, Chan S, Chang H, Li G, Tu Y, Tseng H, et al.
Breast Cancer Res
. 2018 Apr;
20(1):25.
PMID: 29661250
Background: The isocitrate dehydrogenase (IDH) gene family expresses key functional metabolic enzymes in the Krebs cycle and mediates the epigenetic reprogramming, which serves as an important biomarker of breast cancer....
6.
Wang K, Kang C, Tsai C, Chou N, Tu Y, Li G, et al.
Oncol Lett
. 2017 Dec;
15(1):278-284.
PMID: 29285192
A sixth base, 5-hydroxymethylcytosine (5hmC), is formed by the oxidation of 5-methylcytosine (5mC) via the catalysis of the ten-eleven translocation (TET) protein family in cells. Expression levels of 5hmC are...
7.
Huang J, Yang C, Wang J, Liou H, Hsieh I, Li G, et al.
Oncotarget
. 2017 Nov;
8(48):84237-84247.
PMID: 29137419
Buccal mucosa squamous cell carcinoma (BMSCC) is the most common oral cancer in Southeast Asia. Caspase-3, a key molecule in regulating apoptosis, promotes the malignancy of various cancers. However, its...
8.
Peng L, Yuan X, Zhang C, Ye F, Zhou H, Li W, et al.
Oncotarget
. 2017 Apr;
8(21):34387-34397.
PMID: 28415739
Transforming growth factor beta (TGF-β) promotes the pathogenesis of hepatocellular carcinoma (HCC). We evaluated the associations between TGF-β1 expression and clinicopathological parameters in HCC patients from The Cancer Genome Atlas...
9.
Sorenson O, Assenova V, Li G, Boada J, Fleming L
Science
. 2016 Dec;
354(6319):1526-1528.
PMID: 28008025
No abstract available.
10.
Peng L, Yuan X, Liu Z, Li W, Zhang C, Zhang Y, et al.
Oncotarget
. 2016 Dec;
8(1):1655-1667.
PMID: 27926484
Upregulation of lncRNA H19 expression is associated with an unfavorable prognosis in some cancers. However, the prognostic value of H19 in female-specific cancers has remained uncharacterized. In this study, the...