Grisilda Bakiasi
Overview
Explore the profile of Grisilda Bakiasi including associated specialties, affiliations and a list of published articles.
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Articles
6
Citations
458
Followers
0
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Recent Articles
1.
Yeganeh P, Kwak S, Jorfi M, Koler K, Kalatturu T, von Maydell D, et al.
Neuron
. 2024 Nov;
113(2):205-224.e8.
PMID: 39610246
Alzheimer's disease (AD) presents a complex pathological landscape, posing challenges to current therapeutic strategies that primarily target amyloid-β (Aβ). Using a novel integrative pathway activity analysis (IPAA), we identified 83...
2.
Mondal P, Bai P, Gomm A, Bakiasi G, Lin C, Wang Y, et al.
Adv Sci (Weinh)
. 2023 Nov;
11(1):e2304545.
PMID: 37990786
Histone deacetylase 6 (HDAC6) is one of the key histone deacetylases (HDACs) that regulates various cellular functions including clearance of misfolded protein and immunological responses. Considerable evidence suggests that HDAC6...
3.
Kim E, Kim H, Jedrychowski M, Bakiasi G, Park J, Kruskop J, et al.
Neuron
. 2023 Sep;
111(22):3619-3633.e8.
PMID: 37689059
A pathological hallmark of Alzheimer's disease (AD) is the deposition of amyloid-β (Aβ) protein in the brain. Physical exercise has been shown to reduce Aβ burden in various AD mouse...
4.
Zhang S, Bai P, Lei D, Liang Y, Zhen S, Bakiasi G, et al.
J Biol Chem
. 2022 Mar;
298(4):101794.
PMID: 35248531
Epigenetic regulation plays substantial roles in human pathophysiology, which provides opportunities for intervention in human disorders through the targeting of epigenetic pathways. Recently, emerging evidence from preclinical studies suggested the...
5.
Muffat J, Li Y, Omer A, Durbin A, Bosch I, Bakiasi G, et al.
Proc Natl Acad Sci U S A
. 2018 Jun;
115(27):7117-7122.
PMID: 29915057
Maternal Zika virus (ZIKV) infection during pregnancy is recognized as the cause of an epidemic of microcephaly and other neurological anomalies in human fetuses. It remains unclear how ZIKV accesses...
6.
Muffat J, Li Y, Yuan B, Mitalipova M, Omer A, Corcoran S, et al.
Nat Med
. 2016 Nov;
22(11):1358-1367.
PMID: 27668937
Microglia, the only lifelong resident immune cells of the central nervous system (CNS), are highly specialized macrophages that have been recognized to have a crucial role in neurodegenerative diseases such...