Gregory W Konat
Overview
Explore the profile of Gregory W Konat including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
29
Citations
412
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Konat G
Brain Res
. 2024 Sep;
1846:149239.
PMID: 39284559
Peripheral viral infections are well known to profoundly alter brain function; however detailed mechanisms of this immune-to-brain communication have not been deciphered. This review focuses on studies of cerebral effects...
2.
Petrisko T, Konat G
Metab Brain Dis
. 2021 Aug;
36(7):1995-2002.
PMID: 34406561
Peripheral viral infection can substantially alter brain function. We have previously shown that intraperitoneal (i.p.) injection of a viral mimetic, polyinosinic-polycytidylic acid (PIC), engenders hyperexcitability of cerebral neurons. Because neuronal...
3.
Petrisko T, Bloemer J, Pinky P, Srinivas S, Heslin R, Du Y, et al.
Front Neurosci
. 2020 Apr;
14:220.
PMID: 32265633
Peripheral infections can potently exacerbate neuropathological conditions, though the underlying mechanisms are poorly understood. We have previously demonstrated that intraperitoneal (i.p.) injection of a viral mimetic, polyinosinic-polycytidylic acid (PIC) induces...
4.
Petrisko T, Konat G
Metab Brain Dis
. 2019 Jan;
34(2):675-679.
PMID: 30637619
Peripheral viral infections are potent triggers of exacerbation in multiple sclerosis (MS). Here, we used a preclinical model of MS, the experimental autoimmune encephalomyelitis (EAE) to corroborate this comorbidity in...
5.
Hunsberger H, Konat G, Reed M
J Neurochem
. 2017 Mar;
141(3):341-346.
PMID: 28244106
Peripheral viral infections increase seizure propensity and intensity in susceptible individuals. We have modeled this comorbidity by demonstrating that the acute phase response instigated by an intraperitoneal (i.p.) injection of...
6.
Hunsberger H, Wang D, Petrisko T, Alhowail A, Setti S, Suppiramaniam V, et al.
J Neurochem
. 2016 May;
138(2):307-16.
PMID: 27168075
Peripheral infections increase the propensity and severity of seizures in susceptible populations. We have previously shown that intraperitoneal injection of a viral mimic, polyinosinic-polycytidylic acid (PIC), elicits hypersusceptibility of mice...
7.
Michalovicz L, Lally B, Konat G
J Neuroimmunol
. 2015 Jul;
285:137-42.
PMID: 26198930
Peripheral challenge with a viral mimetic, polyinosinic-polycytidylic acid (PIC) induces hippocampal hyperexcitability in mice. Here, we characterized this hippocampal response through a whole genome transcriptome analysis. Intraperitoneal injection of PIC...
8.
Michalovicz L, Konat G
Metab Brain Dis
. 2013 Dec;
29(1):75-86.
PMID: 24363211
We have previously shown that peripherally restricted acute phase response (APR) elicited by intraperitoneal (i.p.) injection of a viral mimic, polyinosinic-polycytidylic acid (PIC), renders the brain hypersusceptible to excitotoxic insult...
9.
Konat G, Lally B, Toth A, Salm A
Metab Brain Dis
. 2011 Jun;
26(3):237-40.
PMID: 21643765
Inflammatory factors associated with immune challenge during early brain development are now firmly implicated in the etiologies of schizophrenia, autism and mood disorders later in life. In rodent models, maternal...
10.
Kirschman L, Borysiewicz E, Fil D, Konat G
Metab Brain Dis
. 2011 Feb;
26(1):91-3.
PMID: 21305346
Clinical evidence implicates peripheral inflammatory diseases as comorbid factors in epilepsy. The present study was designed to determine the effect of the acute phase of antiviral response on seizure susceptibility....