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Gregory M Dick

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Articles 55
Citations 1331
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Recent Articles
1.
Tucker S, Essajee S, Warne C, Dick G, Goulopoulou S, Tune J
J Vasc Res . 2024 Dec; 1-10. PMID: 39662079
Introduction: This study was designed to test the hypothesis that coronary artery adaptations during the postpartum period are related to underlying reductions in endothelium-dependent relaxation and/or augmented smooth muscle vasoconstrictor...
2.
Tucker S, Essajee S, Warne C, Dick G, Heard M, Crowe N, et al.
J Mol Cell Cardiol . 2024 Jul; 194:96-104. PMID: 38971217
Understanding of the mechanisms contributing to the increased maternal susceptibility for major adverse cardiovascular events in the postpartum period remains poor. Accordingly, this study tested the hypothesis that the balance...
3.
Tune J, Warne C, Essajee S, Tucker S, Figueroa C, Dick G, et al.
J Mol Cell Cardiol . 2024 Apr; 190:82-91. PMID: 38608928
The coronary circulation has the inherent ability to maintain myocardial perfusion constant over a wide range of perfusion pressures. The phenomenon of pressure-flow autoregulation is crucial in response to flow-limiting...
4.
Warne C, Essajee S, Tucker S, Figueroa C, Beard D, Dick G, et al.
Basic Res Cardiol . 2023 Mar; 118(1):12. PMID: 36988670
The coronary circulation has an innate ability to maintain constant blood flow over a wide range of perfusion pressures. However, the mechanisms responsible for coronary autoregulation remain a fundamental and...
5.
Tune J, Goodwill A, Baker H, Dick G, Warne C, Tucker S, et al.
Basic Res Cardiol . 2022 Oct; 117(1):50. PMID: 36222894
The lack of pre-clinical large animal models of heart failure with preserved ejection fraction (HFpEF) remains a growing, yet unmet obstacle to improving understanding of this complex condition. We examined...
6.
Goodwill A, Baker H, Dick G, McCallinhart P, Bailey C, Brown S, et al.
Basic Res Cardiol . 2021 May; 116(1):35. PMID: 34018061
Impaired coronary microvascular function (e.g., reduced dilation and coronary flow reserve) predicts cardiac mortality in obesity, yet underlying mechanisms and potential therapeutic strategies remain poorly understood. Mineralocorticoid receptor (MR) antagonism...
7.
Fu L, Jiang G, Weng H, Dick G, Chang Y, Kassab G
Brain Pathol . 2019 Jun; 30(1):92-105. PMID: 31206909
The "two-hit vascular hypothesis for Alzheimer's disease (AD)" and amyloid-β (Aβ) oligomer hypothesis suggest that impaired soluble Aβ oligomers clearance through the cerebral vasculature may be an initial step of...
8.
Kiel A, Goodwill A, Baker H, Dick G, Tune J
Basic Res Cardiol . 2018 Aug; 113(5):33. PMID: 30073416
The local metabolic hypothesis proposes that myocardial oxygen tension determines the degree of autoregulation by increasing the production of vasodilator metabolites as perfusion pressure is reduced. Thus, normal physiologic levels...
9.
Dick G, Namani R, Patel B, Kassab G
Front Physiol . 2018 Jun; 9:580. PMID: 29875686
Myogenic responses (pressure-dependent contractions) of coronary arterioles play a role in autoregulation (relatively constant flow vs. pressure). Publications on myogenic reactivity in swine coronaries vary in caliber, analysis, and degree...
10.
Dick G, Tune J
Circ Res . 2017 Sep; 121(6):594-595. PMID: 28860314
No abstract available.