Gregory Ladics
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Explore the profile of Gregory Ladics including associated specialties, affiliations and a list of published articles.
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14
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94
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Recent Articles
1.
Lee I, Forreryd A, Na M, Schember I, Lavelle M, Gradin R, et al.
ALTEX
. 2025 Jan;
PMID: 39871732
Potency and quantitative risk assessment are essential for determining safe concentrations for the formulation of potential skin sensitizers into consumer products. Several new approach methodologies (NAMs) for skin sensitization hazard...
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Donthamsetty S, Forreryd A, Sterchele P, Huang X, Gradin R, Johansson H, et al.
Regul Toxicol Pharmacol
. 2024 Mar;
149:105597.
PMID: 38460723
Development of New Approach Methodologies (NAMs) capable of providing a No Expected Sensitization Induction Level (NESIL) value remains a high priority for the fragrance industry for conducting a Quantitative Risk...
4.
Smits M, Meijerink M, Le T, Knulst A, de Jong A, Caspers M, et al.
BMC Immunol
. 2021 Apr;
22(1):27.
PMID: 33849432
Background: Food proteins differ in their allergenic potential. Currently, there is no predictive and validated bio-assay to evaluate the allergenicity of novel food proteins. The objective of this study was...
5.
Akkerdaas J, Totis M, Barnett B, Bell E, Davis T, Edrington T, et al.
Clin Transl Allergy
. 2018 Aug;
8:30.
PMID: 30116520
Background: Susceptibility to pepsin digestion of candidate transgene products is regarded an important parameter in the weight-of-evidence approach for allergenicity risk assessment of genetically modified crops. It has been argued...
6.
McClain S, Jones W, He X, Ladics G, Bartholomaeus A, Raybould A, et al.
Zhonghua Yu Fang Yi Xue Za Zhi
. 2015 Apr;
49(1):78-87.
PMID: 25876504
Genetically modified (GM) crops were first introduced to farmers in 1995 with the intent to provide better crop yield and meet the increasing demand for food and feed. GM crops...
7.
Privalle L, Bannon G, Herman R, Ladics G, McClain S, Stagg N, et al.
Regul Toxicol Pharmacol
. 2011 Sep;
61(3):292-5.
PMID: 21906650
Thermal stability has been reported as a shared characteristic among some of the major food allergens and appears to have originated from the observation that some cooked foods retain their...
8.
Doerrer N, Ladics G, McClain S, Herouet-Guicheney C, Poulsen L, Privalle L, et al.
Regul Toxicol Pharmacol
. 2010 Jul;
58(3 Suppl):S2-7.
PMID: 20615445
The International Life Sciences Institute Health and Environmental Sciences Institute Protein Allergenicity Technical Committee hosted an international workshop November 16-17, 2009, in Paris, France, with over 60 participants from academia,...
9.
Thomas K, MacIntosh S, Bannon G, Herouet-Guicheney C, Holsapple M, Ladics G, et al.
Food Chem Toxicol
. 2009 May;
47(6):1041-50.
PMID: 19425225
The safety assessment of genetically modified crops includes the evaluation for potential allergenicity. The current 'state-of-the-science' utilizes a weight of evidence approach, as outlined by the Codex Alimentarius commission (Alinorm...
10.
Cressman R, Ladics G
Regul Toxicol Pharmacol
. 2008 Dec;
54(3 Suppl):S20-5.
PMID: 19114081
FAO/WHO has recommended that IgE cross-reactivity between a transgenic protein and allergen be considered when there is greater than 35% identity over a sliding "window" of 80 amino acids. In...