Gregory J Atkins
Overview
Explore the profile of Gregory J Atkins including associated specialties, affiliations and a list of published articles.
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Articles
14
Citations
156
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Recent Articles
1.
Atkins G, Sheahan B
J Gen Virol
. 2016 Mar;
97(6):1283-1296.
PMID: 27028153
Alphaviruses are enveloped viruses with a positive-stranded RNA genome, of the family Togaviridae. In mammals and birds they are mosquito-transmitted and are of veterinary and medical importance. They cause primarily...
2.
Piggott J, Sheahan B, Soden D, OSullivan G, Atkins G
Mol Med Rep
. 2011 Apr;
2(5):753-6.
PMID: 21475897
Electroporation is the application of high-voltage short-duration pulses to transiently permeabilize cells, permitting the cellular uptake of macromolecules, including nucleic acid. Although much attention has been focused on DNA vaccines,...
3.
Atkins G, Fleeton M, Sheahan B
Expert Rev Mol Med
. 2008 Nov;
10:e33.
PMID: 19000329
Alphavirus vectors are high-level, transient expression vectors for therapeutic and prophylactic use. These positive-stranded RNA vectors, derived from Semliki Forest virus, Sindbis virus and Venezuelan equine encephalitis virus, multiply and...
4.
Logue C, Sheahan B, Atkins G
Virus Genes
. 2008 Feb;
36(2):313-21.
PMID: 18264748
An investigation of the role of the 5' untranslated region (UTR) of Semliki Forest virus (SFV) in determining pathogenicity in infected mice was carried out by constructing 5' UTR chimeras....
5.
Kelly B, Fleeton M, Atkins G
Recent Pat Anticancer Drug Discov
. 2008 Jan;
2(2):159-66.
PMID: 18221060
Alphaviruses are positive-strand RNA viruses that are being developed as a high level transient expression vectors. Although most work so far has centered on their use as vaccine vectors, they...
6.
Callagy S, Kelly B, Fleeton M, Sheahan B, Galbraith S, Atkins G
Vaccine
. 2007 Oct;
25(43):7481-90.
PMID: 17905485
A Semliki Forest virus (SFV) recombinant particle vaccine vector was constructed expressing the viral E1 and E2 envelope proteins of the RA27/3 vaccine strain of rubella virus. This vector induced...
7.
Galbraith S, Sheahan B, Atkins G
J Gen Virol
. 2006 Mar;
87(Pt 4):937-947.
PMID: 16528043
Major virulence determinants of Semliki Forest virus (SFV) lie within the non-structural genes that form the replicase complex proteins. Gene exchange between virulent and avirulent viruses has shown that the...
8.
Greene L, Fleeton M, Mulligan J, Gowda C, Sheahan B, Atkins G, et al.
Oncol Rep
. 2005 Oct;
14(5):1357-63.
PMID: 16211309
Members of a novel series of pyrrolo-1,5-benzoxazepine (PBOX) compounds have been shown to induce apoptosis in a number of human leukemia cell lines of different haematological lineage, suggesting their potential...
9.
Atkins G, Smyth J, Fleeton M, Galbraith S, Sheahan B
Curr Cancer Drug Targets
. 2004 Dec;
4(7):597-607.
PMID: 15578917
The alphaviruses Semliki Forest virus (SFV) and Sindbis virus have recently been developed as prototype anti-cancer agents. These are RNA-containing enveloped viruses that code for only 9 proteins of unique...
10.
Atkins G, Cosby S
Crit Rev Immunol
. 2004 Jan;
23(4):323-38.
PMID: 14700273
The measles-mumps-rubella (MMR) vaccine has been very effective in the elimination of disease and has high biosafety. However, it has been associated with several adverse effects and has recently caused...