Gregory H Nielsen
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Explore the profile of Gregory H Nielsen including associated specialties, affiliations and a list of published articles.
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Recent Articles
1.
Nielsen G, Sachs J, Hackel B
Biotechnol Bioeng
. 2025 Mar;
PMID: 40045532
Protein developability is an important, yet often overlooked, aspect of protein discovery campaigns that is a key driver of utility. Recent advances have improved developability screening capacity, making it an...
2.
Nielsen G, Schmitz Z, Hackel B
Protein Eng Des Sel
. 2024 Jun;
37.
PMID: 38836499
Protein developability is requisite for use in therapeutic, diagnostic, or industrial applications. Many developability assays are low throughput, which limits their utility to the later stages of protein discovery and...
3.
Golinski A, Schmitz Z, Nielsen G, Johnson B, Saha D, Appiah S, et al.
ACS Synth Biol
. 2023 Aug;
12(9):2600-2615.
PMID: 37642646
Engineered proteins have emerged as novel diagnostics, therapeutics, and catalysts. Often, poor protein developability─quantified by expression, solubility, and stability─hinders utility. The ability to predict protein developability from amino acid sequence...