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Gregory G Mahairas

Explore the profile of Gregory G Mahairas including associated specialties, affiliations and a list of published articles. Areas
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Articles 11
Citations 348
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Recent Articles
1.
Thomson K, Odom G, Murry C, Mahairas G, Moussavi-Harami F, Teichman S, et al.
JACC Basic Transl Sci . 2017 May; 1(7):666-679. PMID: 28553667
Despite recent advances, chronic heart failure remains a significant and growing unmet medical need, reaching epidemic proportions carrying substantial morbidity, mortality, and costs. A safe and convenient therapeutic agent that...
2.
Kolwicz Jr S, Odom G, Nowakowski S, Moussavi-Harami F, Chen X, Reinecke H, et al.
Mol Ther . 2015 Sep; 24(2):240-250. PMID: 26388461
Impaired systolic function, resulting from acute injury or congenital defects, leads to cardiac complications and heart failure. Current therapies slow disease progression but do not rescue cardiac function. We previously...
3.
Awasthi S, Mahairas G, Shaw C, Huang M, Koelle D, Posavad C, et al.
J Virol . 2015 Jun; 89(16):8497-509. PMID: 26041292
Unlabelled: We evaluated a genital herpes prophylactic vaccine containing herpes simplex virus 2 (HSV-2) glycoproteins C (gC2) and D (gD2) to stimulate humoral immunity and UL19 (capsid protein VP5) and...
4.
Kadota S, Carey J, Reinecke H, Leggett J, Teichman S, Laflamme M, et al.
Eur J Heart Fail . 2015 Apr; 17(8):772-81. PMID: 25876005
Aims: Heart failure remains a leading cause of morbidity, hospitalizations, and deaths. We previously showed that overexpression of the enzyme ribonucleotide reductase (RNR) in cardiomyocytes increased levels of the myosin...
5.
Minion F, Lefkowitz E, Madsen M, Cleary B, Swartzell S, Mahairas G
J Bacteriol . 2004 Oct; 186(21):7123-33. PMID: 15489423
We present the complete genome sequence of Mycoplasma hyopneumoniae, an important member of the porcine respiratory disease complex. The genome is composed of 892,758 bp and has an average G+C...
6.
Breen M, Hitte C, Lorentzen T, Thomas R, Cadieu E, Sabacan L, et al.
BMC Genomics . 2004 Sep; 5:65. PMID: 15363096
Background: The 156 breeds of dog recognized by the American Kennel Club offer a unique opportunity to map genes important in genetic variation. Each breed features a defining constellation of...
7.
Munson Jr R, Zhong H, Mungur R, Ray W, Shea R, Mahairas G, et al.
Infect Immun . 2004 Jan; 72(2):1143-6. PMID: 14742562
The nucleotide sequence of pNAD1, a plasmid from Haemophilus ducreyi identified on the basis of its ability to confer NAD independence on Actinobacillus pleuropneumoniae and H. influenzae, has been determined....
8.
Guyon R, Lorentzen T, Hitte C, Kim L, Cadieu E, Parker H, et al.
Proc Natl Acad Sci U S A . 2003 Apr; 100(9):5296-301. PMID: 12700351
The purebred dog population consists of >300 partially inbred genetic isolates or breeds. Restriction of gene flow between breeds, together with strong selection for traits, has led to the establishment...
9.
Minion F, Menon S, Mahairas G, Wannemuehler M
Infect Immun . 2003 Mar; 71(4):2239-43. PMID: 12654848
The Mycobacterium tuberculosis protein ESAT-6 has unusual immune stimulating activities, has been implicated in the recall of long-lived immunity, and induces protection against tuberculosis in mice. For many diseases caused...
10.
Menon S, Wannemuehler M, Mahairas G, Minion F
J Interferon Cytokine Res . 2002 Aug; 22(7):807-13. PMID: 12184919
Type 1 immune responses play an important role in the resolution of diseases with infectious or oncogenic etiologies. Vaccines for production animals frequently target humoral immune responses and are often...