Gregory E Conner
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Explore the profile of Gregory E Conner including associated specialties, affiliations and a list of published articles.
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39
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1280
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Recent Articles
1.
Conner G
Redox Biol
. 2024 Jun;
75:103251.
PMID: 38936256
Hydrogen peroxide is a key element in redox signaling and in setting cellular redox tone. DUOX1 and DUOX2, that directly synthesize hydrogen peroxide, are the most abundant NADPH oxidase transcripts...
2.
Conner G
Redox Biol
. 2021 Mar;
41:101931.
PMID: 33743241
Redox status is a central determinant of cellular activities and redox imbalance is correlated with numerous diseases. NADPH oxidase activity results in formation of HO, that, in turn, sets cellular...
3.
Burgueno J, Fritsch J, Gonzalez E, Landau K, Santander A, Fernandez I, et al.
Gastroenterology
. 2020 Oct;
160(3):797-808.e6.
PMID: 33127391
Background & Aims: Chronic colonic inflammation leads to dysplasia and cancer in patients with inflammatory bowel disease. We have described the critical role of innate immune signaling via Toll-like receptor...
4.
Burgueno J, Fritsch J, Santander A, Brito N, Fernandez I, Pignac-Kobinger J, et al.
Front Physiol
. 2019 Dec;
10:1484.
PMID: 31871440
The microbes in the gastrointestinal tract are separated from the host by a single layer of intestinal epithelial cells (IECs) that plays pivotal roles in maintaining homeostasis by absorbing nutrients...
5.
Gattas M, Jaffe A, Barahona J, Conner G
Redox Biol
. 2019 Nov;
28:101346.
PMID: 31678720
The NADPH oxidase reaction produces protons. In the case of the NADPH oxidase, NOX2, activity depends on secretion of these protons and is inhibited by blockade of the voltage-gated proton...
6.
Kerr N, de Rivero Vaccari J, Umland O, Ross Bullock M, Conner G, Dietrich W, et al.
Cells
. 2019 Jan;
8(1).
PMID: 30669285
Approximately 30% of traumatic brain injured patients suffer from acute lung injury or acute respiratory distress syndrome. Our previous work revealed that extracellular vesicle (EV)-mediated inflammasome signaling plays a crucial...
7.
Valencia-Gattas M, Conner G, Fregien N
PLoS One
. 2016 Aug;
11(8):e0160216.
PMID: 27532261
Cigarette smoke exposure is a major health hazard. Ciliated cells in the epithelium of the airway play a critical role in protection against the noxious effects of inhaled cigarette smoke....
8.
Dahl G, Conner G, Qiu F, Wang J, Spindler E, Campagna J, et al.
EBioMedicine
. 2016 Jun;
10:291-7.
PMID: 27349457
Research In Context: Clevidipine lowers blood pressure by inhibiting calcium channels in vascular smooth muscle. In patients with acute heart failure, clevidipine was shown to relieve breathing problems. This was...
9.
Ivonnet P, Unwalla H, Salathe M, Conner G
Respir Res
. 2016 Feb;
17:15.
PMID: 26857816
Background: Elevated H2O2 levels are associated with inflammatory diseases and H2O2 exposure is known to disrupt epithelial barrier function, leading to increased permeability and decreased electrical resistance. In normal human...
10.
Adams K, Abraham V, Spielman D, Kolls J, Rubenstein R, Conner G, et al.
PLoS One
. 2014 Aug;
9(8):e103263.
PMID: 25141009
The epithelium plays an active role in the response to inhaled pathogens in part by responding to signals from the immune system. Epithelial responses may include changes in chemokine expression,...