Gregory A OSullivan
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Explore the profile of Gregory A OSullivan including associated specialties, affiliations and a list of published articles.
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Articles
14
Citations
574
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0
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Recent Articles
1.
Poon A, Saini H, Sethi S, OSullivan G, Plun-Favreau H, Wray S, et al.
Stem Cell Reports
. 2021 Apr;
16(5):1276-1289.
PMID: 33891871
Sequestosome-1 (SQSTM1/p62) is involved in cellular processes such as autophagy and metabolic reprogramming. Mutations resulting in the loss of function of SQSTM1 lead to neurodegenerative diseases including frontotemporal dementia. The...
2.
Scott H, Buckner N, Fernandez-Albert F, Pedone E, Postiglione L, Shi G, et al.
J Biol Chem
. 2020 Apr;
295(17):5835.
PMID: 32332132
No abstract available.
3.
Scott H, Buckner N, Fernandez-Albert F, Pedone E, Postiglione L, Shi G, et al.
J Biol Chem
. 2020 Jan;
295(10):3285-3300.
PMID: 31911436
Genetic and biochemical evidence points to an association between mitochondrial dysfunction and Parkinson's disease (PD). PD-associated mutations in several genes have been identified and include those encoding PTEN-induced putative kinase...
4.
Soutar M, Kempthorne L, Miyakawa S, Annuario E, Melandri D, Harley J, et al.
Sci Rep
. 2018 Jun;
8(1):8855.
PMID: 29891871
The discovery of mutations within genes associated with autosomal recessive Parkinson's disease allowed for the identification of PINK1/Parkin regulated mitophagy as an important pathway for the removal of damaged mitochondria....
5.
OSullivan G, Jedlicka P, Chen H, Kalbouneh H, Ippolito A, Deller T, et al.
Mol Cell Neurosci
. 2016 Feb;
72:101-13.
PMID: 26829712
Mutations that result in the defective trafficking of γ2 subunit containing GABAA receptors (γ2-GABAARs) are known to reduce synaptic inhibition. Whether perturbed clustering of non-mutated GABAARs similarly reduces synaptic inhibition...
6.
Pan-Montojo F, Schwarz M, Winkler C, Arnhold M, OSullivan G, Pal A, et al.
Sci Rep
. 2012 Dec;
2:898.
PMID: 23205266
Pathological studies on Parkinson's disease (PD) patients suggest that PD pathology progresses from the enteric nervous system (ENS) and the olfactory bulb into the central nervous system. We have previously...
7.
Galvez T, Gilleron J, Zerial M, OSullivan G
Cell
. 2012 Oct;
151(1):234-234.e2.
PMID: 23021225
No abstract available.
8.
Weltzien F, Puller C, OSullivan G, Paarmann I, Betz H
J Comp Neurol
. 2012 May;
520(17):3962-81.
PMID: 22592841
Inhibitory glycine receptors (GlyRs) are composed of homologous α- (α1-4) and β-subunits. The β-subunits (GlyRβ) interact via their large cytosolic loops with the postsynaptic scaffolding protein gephyrin and are therefore...
9.
Bausen M, Weltzien F, Betz H, OSullivan G
Mol Cell Neurosci
. 2010 Mar;
44(3):201-9.
PMID: 20206270
The scaffolding protein gephyrin is essential for the clustering of glycine and GABA(A) receptors (GABA(A)Rs) at inhibitory synapses. Here, we provide evidence that the size of the postsynaptic gephyrin scaffold...
10.
Reining S, Gisler S, Fuster D, Moe O, OSullivan G, Betz H, et al.
Am J Physiol Renal Physiol
. 2009 Feb;
296(5):F1118-28.
PMID: 19225049
Renal reabsorption of inorganic phosphate (P(i)) is mainly mediated by the Na(+)-dependent P(i)-cotransporter NaPi-IIa that is expressed in the brush-border membrane (BBM) of renal proximal tubules. Regulation and apical expression...