Gregor Eichele
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Explore the profile of Gregor Eichele including associated specialties, affiliations and a list of published articles.
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71
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6293
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Recent Articles
1.
Raghavan V, Eichele G, Larink O, Levy Karin E, Soding J
NAR Genom Bioinform
. 2023 Feb;
5(1):lqad007.
PMID: 36814456
Zooplankton are important eukaryotic constituents of marine ecosystems characterized by limited motility in the water. These metazoans predominantly occupy intermediate trophic levels and energetically link primary producers to higher trophic...
2.
Ditte Z, Silbern I, Ditte P, Urlaub H, Eichele G
J Extracell Vesicles
. 2022 Nov;
11(11):e12276.
PMID: 36325603
The choroid plexus secrets cerebrospinal fluid (CSF) composed of electrolytes, cytokines, growth factors, metabolites and extracellular vesicles (EVs) that flow through the interconnected brain ventricles. On their course, CSF components...
3.
Michurina A, Sakib M, Kerimoglu C, Kruger D, Kaurani L, Islam M, et al.
EMBO J
. 2021 Nov;
41(1):e106459.
PMID: 34806773
In mammals, histone 3 lysine 4 methylation (H3K4me) is mediated by six different lysine methyltransferases. Among these enzymes, SETD1B (SET domain containing 1b) has been linked to syndromic intellectual disability...
4.
Martinez Hernandez A, Silbern I, Geffers I, Tatenhorst L, Becker S, Urlaub H, et al.
Front Neurosci
. 2021 Jul;
15:643391.
PMID: 34220415
α-synuclein (αSyn) is the main protein component of Lewy bodies, intracellular inclusions found in the brain of Parkinson's disease (PD) patients. Neurotoxic αSyn species are broadly modified post-translationally and, in...
5.
Hubbard J, Kobayashi Frisk M, Ruppert E, Tsai J, Fuchs F, Robin-Choteau L, et al.
Proc Natl Acad Sci U S A
. 2021 Jun;
118(25).
PMID: 34155139
Artificial lighting, day-length changes, shift work, and transmeridian travel all lead to sleep-wake disturbances. The nychthemeral sleep-wake cycle (SWc) is known to be controlled by output from the central circadian...
6.
Ulmke P, Sakib M, Ditte P, Sokpor G, Kerimoglu C, Pham L, et al.
Stem Cell Reports
. 2021 Apr;
16(4):968-984.
PMID: 33798452
Intermediate progenitor cells (IPCs) are neocortical neuronal precursors. Although IPCs play crucial roles in corticogenesis, their molecular features remain largely unknown. In this study, we aimed to characterize the molecular...
7.
Chongtham M, Wang H, Thaller C, Hsiao N, Vachkov I, Pavlov S, et al.
Front Cell Dev Biol
. 2020 Dec;
8:584314.
PMID: 33344448
The main stem cell niche for neurogenesis in the adult mammalian brain is the subventricular zone (SVZ) that extends along the cerebral lateral ventricles. We aimed at characterizing the initial...
8.
Ajam T, De I, Petkau N, Whelan G, Pena V, Eichele G
Sci Rep
. 2020 Jun;
10(1):9828.
PMID: 32555289
Cohesin is a protein complex whose core subunits, Smc1, Smc3, Scc1, and SA1/SA2 form a ring-like structure encircling the DNA. Cohesins play a key role in the expression, repair, and...
9.
McNicoll F, Kuhnel A, Biswas U, Hempel K, Whelan G, Eichele G, et al.
Life Sci Alliance
. 2020 Feb;
3(3).
PMID: 32051254
In mitotic cells, establishment of sister chromatid cohesion requires acetylation of the cohesin subunit SMC3 (acSMC3) by ESCO1 and/or ESCO2. Meiotic cohesin plays additional but poorly understood roles in the...
10.
Eichele G, Bodenschatz E, Ditte Z, Gunther A, Kapoor S, Wang Y, et al.
Philos Trans R Soc Lond B Biol Sci
. 2019 Dec;
375(1792):20190154.
PMID: 31884922
The brain ventricles are interconnected, elaborate cavities that traverse the brain. They are filled with cerebrospinal fluid (CSF) that is, to a large part, produced by the choroid plexus, a...