Gregor B Adams
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Explore the profile of Gregor B Adams including associated specialties, affiliations and a list of published articles.
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27
Citations
1346
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Recent Articles
1.
Bassan D, Weinberger L, Yi J, Kim T, Weist M, Adams G, et al.
J Immunother Cancer
. 2023 Dec;
11(12).
PMID: 38097342
Background: One of the major challenges in chimeric antigen receptor (CAR)-T cell therapy for solid tumors is the potential for on-target off-tumor toxicity due to the expression of CAR tumor...
2.
Zhou X, Crow A, Hartiala J, Spindler T, Ghazalpour A, Barsky L, et al.
Stem Cell Reports
. 2015 Jun;
5(1):125-38.
PMID: 26050929
Prior efforts to identify regulators of hematopoietic stem cell physiology have relied mainly on candidate gene approaches with genetically modified mice. Here we used a genome-wide association study (GWAS) strategy...
3.
Cheng C, Adams G, Perin L, Wei M, Zhou X, Lam B, et al.
Cell Stem Cell
. 2014 Jun;
14(6):810-23.
PMID: 24905167
Immune system defects are at the center of aging and a range of diseases. Here, we show that prolonged fasting reduces circulating IGF-1 levels and PKA activity in various cell...
4.
Spindler T, Tseng A, Zhou X, Adams G
Stem Cells Dev
. 2013 Oct;
23(4):434-41.
PMID: 24083324
Mesenchymal stem cells (MSCs), as well as osteoblastic cells derived from these MSCs, have been shown to be key components of the hematopoietic stem cell (HSC) niche. In this study,...
5.
Zhou X, Barsky L, Adams G
PLoS One
. 2013 Aug;
8(8):e67861.
PMID: 23936296
Two distinct microenvironmental niches that regulate hematopoietic stem/progenitor cell physiology in the adult bone marrow have been proposed; the endosteal and the vascular niche. While extensive studies have been performed...
6.
Luo B, Tseng C, Adams G, Lee A
Stem Cells Dev
. 2013 Jul;
22(23):3062-73.
PMID: 23859598
We have previously reported that acute inducible knockout of the endoplasmic reticulum chaperone GRP94 led to an expansion of the hematopoietic stem and progenitor cell pool. Here, we investigated the...
7.
8.
Luo B, Lam B, Lee S, Wey S, Zhou H, Wang M, et al.
PLoS One
. 2011 Jun;
6(5):e20364.
PMID: 21647226
Hematopoietic stem cell (HSC) homeostasis in the adult bone marrow (BM) is regulated by both intrinsic gene expression products and interactions with extrinsic factors in the HSC niche. GRP94, an...
9.
Lam B, Adams G
Cell Stem Cell
. 2011 Apr;
8(4):354-6.
PMID: 21474097
Selective targeting of cancer stem cells (CSCs) has the potential to prevent cancer relapse. Wang et al. (2011) report that hypoxia-inducible factor 1α (HIF1α) represses Notch signaling to maintain CSC...
10.
Wren T, Chung S, Dorey F, Bluml S, Adams G, Gilsanz V
J Clin Endocrinol Metab
. 2010 Dec;
96(3):782-6.
PMID: 21177790
Objective: Recent studies suggest a close local link between bone marrow adiposity and endosteal bone formation. Using magnetic resonance imaging, we examined whether the relation between the amount of marrow...