Gregor B Adams
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Explore the profile of Gregor B Adams including associated specialties, affiliations and a list of published articles.
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27
Citations
1346
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Recent Articles
11.
Lam B, Cunningham C, Adams G
Blood
. 2010 Nov;
117(4):1167-75.
PMID: 21076044
The ability of hematopoietic stem cells (HSCs) to undergo self-renewal is partly regulated by external signals originating from the stem cell niche. Our previous studies with HSCs obtained from fetal...
12.
Lam B, Adams G
Int J Lab Hematol
. 2010 Aug;
32(6 Pt 2):551-8.
PMID: 20682000
Treatment of malignant blood disorders, such as leukemia, that can provide a better chance of long-term remission involves myeloablation followed by transplantation of matched donor hematopoietic stem cells (HSCs). For...
13.
14.
Rashidi N, Adams G
Curr Osteoporos Rep
. 2009 Jul;
7(2):53-7.
PMID: 19631029
Adult hematopoietic stem cells (HSCs) reside in the bone marrow in stable microenvironments known as the stem cell niche. One key component of the stem cell niche is cells of...
15.
Adams G, Alley I, Chung U, Chabner K, Jeanson N, Lo Celso C, et al.
Nature
. 2009 Mar;
459(7243):103-7.
PMID: 19322176
Haematopoietic stem and progenitor cells (HSPCs) change location during development and circulate in mammals throughout life, moving into and out of the bloodstream to engage bone marrow niches in sequential...
16.
Adams G
Cell Stem Cell
. 2008 Oct;
3(4):361-2.
PMID: 18940726
In this issue of Cell Stem Cell, Viatour et al. (2008) delete all three members of the retinoblastoma tumor suppressor gene family in hematopoietic stem cells, resulting in a myeloproliferative...
17.
Larsson J, Ohishi M, Garrison B, Aspling M, Janzen V, Adams G, et al.
Cell Stem Cell
. 2008 Aug;
3(2):221-7.
PMID: 18682243
Stem cell population size is highly regulated across species and tissue types, and alterations are associated with premature tissue failure or cancer. We assessed whether the tumor suppressor and mediator...
18.
Adams G
Regen Med
. 2008 Jul;
3(4):523-30.
PMID: 18588474
Development of the hematopoietic system is a stage-specific process where the bone marrow eventually becomes the principal source of hematopoiesis in the adult mammalian organism. Sustained hematopoiesis in the bone...
19.
Adams G, Martin R, Alley I, Chabner K, Cohen K, Calvi L, et al.
Nat Biotechnol
. 2007 Jan;
25(2):238-43.
PMID: 17237769
The specialized microenvironment or niche where stem cells reside provides regulatory input governing stem cell function. We tested the hypothesis that targeting the niche might improve stem cell-based therapies using...
20.
Adams G, Scadden D
Nat Immunol
. 2006 Mar;
7(4):333-7.
PMID: 16550195
A signature characteristic of stem cells is their ability to self-renew, affording a theoretically limitless ability to produce daughter cells and their descendents. This near-timeless dimension of stem cell function...