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Greg T Nolen

Explore the profile of Greg T Nolen including associated specialties, affiliations and a list of published articles. Areas
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Recent Articles
1.
Tini G, Varma V, Lombardo R, Nolen G, Lefebvre G, Descombes P, et al.
Genes Nutr . 2020 Nov; 15(1):21. PMID: 33243154
Background: Increased adipogenesis and altered adipocyte function contribute to the development of obesity and associated comorbidities. Fructose modified adipocyte metabolism compared to glucose, but the regulatory mechanisms and consequences for...
2.
Nassiri I, Lombardo R, Lauria M, Morine M, Moyseos P, Varma V, et al.
Sci Rep . 2016 Jul; 6:28851. PMID: 27385551
The investigation of the complex processes involved in cellular differentiation must be based on unbiased, high throughput data processing methods to identify relevant biological pathways. A number of bioinformatics tools...
3.
Varma V, Boros L, Nolen G, Chang C, Wabitsch M, Beger R, et al.
Metabolites . 2015 Jun; 5(2):364-85. PMID: 26087138
Increased consumption of sugar and fructose as sweeteners has resulted in the utilization of fructose as an alternative metabolic fuel that may compete with glucose and alter its metabolism. To...
4.
Varma V, Boros L, Nolen G, Chang C, Wabitsch M, Beger R, et al.
Metabolomics . 2015 May; 11(3):529-544. PMID: 25972768
The development of obesity is becoming an international problem and the role of fructose is unclear. Studies using liver tissue and hepatocytes have contributed to the understanding of fructose metabolism....
5.
Mondal A, Das S, Varma V, Nolen G, McGehee R, Elbein S, et al.
Metab Syndr Relat Disord . 2012 May; 10(4):297-306. PMID: 22545589
The endoplasmic reticulum (ER) of adipocytes plays a major role in the assembly and secretion of adipokines. The levels of serum adiponectin, secreted by adipocytes, are decreased in insulin resistance,...
6.
Finlin B, Varma V, Nolen G, Dube J, Starnes C, Rasouli N, et al.
J Nutr Biochem . 2011 Aug; 23(8):885-91. PMID: 21852085
Macrophages are an important component of muscle where they are involved in complex processes such as repair, regeneration and hypertrophy. We recently reported that macrophage numbers increase in the muscle...
7.
Nagarajan R, Datta S, Scutari M, Beggs M, Nolen G, Peterson C
Front Physiol . 2011 Mar; 1:21. PMID: 21423363
Aging is accompanied by considerable heterogeneity with possible co-expression of differentiation pathways. The present study investigates the interplay between crucial myogenic, adipogenic, and Wnt-related genes orchestrating aged myogenic progenitor differentiation...
8.
Singh S, Vinson C, Gurley C, Nolen G, Beggs M, Nagarajan R, et al.
Am J Pathol . 2010 Sep; 177(4):2055-66. PMID: 20829439
Rhabdomyosarcoma is a primitive neoplasm with a poorly understood etiology that exhibits features of fetal skeletal muscle. It represents the most frequent malignant soft tissue sarcoma affecting the pediatric population...
9.
Varma V, Yao-Borengasser A, Rasouli N, Nolen G, Phanavanh B, Starks T, et al.
Am J Physiol Endocrinol Metab . 2009 Apr; 296(6):E1300-10. PMID: 19336660
Obesity is characterized by adipose tissue expansion as well as macrophage infiltration of adipose tissue. This results in an increase in circulating inflammatory cytokines and nonesterified fatty acids, factors that...
10.
Varma V, Yao-Borengasser A, Bodles A, Rasouli N, Phanavanh B, Nolen G, et al.
Diabetes . 2007 Dec; 57(2):432-9. PMID: 18057090
Objective: We examined the relationship between the expression of thrombospondin (TSP)1, an antiangiogenic factor and regulator of transforming growth factor-beta activity, obesity, adipose inflammation, and insulin resistance. Research Design And...