Greg A Kirchenbaum
Overview
Explore the profile of Greg A Kirchenbaum including associated specialties, affiliations and a list of published articles.
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32
Citations
597
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Recent Articles
1.
Kirchenbaum G, Pawelec G, Lehmann P
Cells
. 2025 Feb;
14(3).
PMID: 39937014
Determining an individual's humoral immune reactivity to a pathogen, autoantigen, or environmental agent is traditionally accomplished through the assessment of specific antibody levels in blood. However, in many instances, titers...
2.
Lehmann P, Karulin A, Becza N, Yao L, Liu Z, Chepke J, et al.
J Immunol Methods
. 2025 Jan;
537:113817.
PMID: 39864733
Owing to their ability to reliably detect even very rare antigen-specific B cells in cellular isolates such as peripheral blood mononuclear cells (PBMC), and doing so robustly in a high...
3.
Carter D, Darby C, Johnson S, Carlock M, Kirchenbaum G, Allen J, et al.
J Virol
. 2024 May;
98(7):e0183223.
PMID: 38819163
No abstract available.
4.
Yao L, Becza N, Maul-Pavicic A, Chepke J, Kirchenbaum G, Lehmann P
Methods Mol Biol
. 2024 Mar;
2768:251-272.
PMID: 38502398
The B lymphocyte response can encompass four immunoglobulin (Ig) classes and four IgG subclasses, each contributing fundamentally different effector functions. Production of the appropriate Ig class/subclass is critical for both...
5.
Becza N, Liu Z, Chepke J, Gao X, Lehmann P, Kirchenbaum G
Methods Mol Biol
. 2024 Mar;
2768:211-239.
PMID: 38502396
The affinity distribution of the antigen-specific memory B cell (B) repertoire in the body is a critical variable that defines an individual's ability to rapidly generate high-affinity protective antibody specificities....
6.
Lehmann P, Liu Z, Becza N, Valente A, Wang J, Kirchenbaum G
Methods Mol Biol
. 2024 Mar;
2768:167-200.
PMID: 38502394
Memory B cells (B) provide the second wall of adaptive humoral host defense upon specific antigen rechallenge when the first wall, consisting of preformed antibodies originating from a preceding antibody...
7.
Karulin A, Katona M, Megyesi Z, Kirchenbaum G, Lehmann P
Methods Mol Biol
. 2024 Mar;
2768:59-85.
PMID: 38502388
Antigen-specific B-cell ELISPOT and multicolor FluoroSpot assays, in which the membrane-bound antigen itself serves as the capture reagent for the antibodies that B cells secrete, inherently result in a broad...
8.
Wolf C, Koppert S, Becza N, Kuerten S, Kirchenbaum G, Lehmann P
Cells
. 2022 Nov;
11(22).
PMID: 36429090
The scope of immune monitoring is to define the existence, magnitude, and quality of immune mechanisms operational in a host. In clinical trials and praxis, the assessment of humoral immunity...
9.
Kirchenbaum G, Sautto G, Richardson R, Ecker J, Ross T
J Virol
. 2021 Sep;
95(23):e0237920.
PMID: 34523961
Influenza remains one of the most contagious infectious diseases. Approximately, 25 to 50 million people suffer from influenza-like illness in the United States annually, leading to almost 1 million hospitalizations....
10.
Koppert S, Wolf C, Becza N, Sautto G, Franke F, Kuerten S, et al.
Cells
. 2021 Aug;
10(8).
PMID: 34440612
Assessment of humoral immunity to SARS-CoV-2 and other infectious agents is typically restricted to detecting antigen-specific antibodies in the serum. Rarely does immune monitoring entail assessment of the memory B-cell...