Grazyna Mosieniak
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Explore the profile of Grazyna Mosieniak including associated specialties, affiliations and a list of published articles.
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44
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1090
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Recent Articles
11.
Gluchowska A, Cysewski D, Baj-Krzyworzeka M, Szatanek R, Weglarczyk K, Podszywalow-Bartnicka P, et al.
Geroscience
. 2022 Jul;
44(6):2863-2884.
PMID: 35900662
Atherosclerosis, a common age-related disease, is characterized by intense immunological activity. Atherosclerotic plaque is composed of endothelial cells, vascular smooth muscle cells (VSMCs), lipids and immune cells infiltrating from the...
12.
Krzystyniak A, Wesierska M, Petrazzo G, Gadecka A, Dudkowska M, Bielak-Zmijewska A, et al.
Aging (Albany NY)
. 2022 Jan;
14(2):572-595.
PMID: 35042834
Aging is associated with cognitive decline and accumulation of senescent cells in various tissues and organs. Senolytic agents such as dasatinib and quercetin (D+Q) in combination have been shown to...
13.
Sikora E, Bielak-Zmijewska A, Mosieniak G
Ageing Res Rev
. 2021 Sep;
71:101458.
PMID: 34500043
Cellular senescence is a stress response, which can be evoked in all type of somatic cells by different stimuli. Senescent cells accumulate in the body and participate in aging and...
14.
Strzeszewska-Potyrala A, Staniak K, Czarnecka-Herok J, Rafiee M, Herok M, Mosieniak G, et al.
Cancers (Basel)
. 2021 Apr;
13(9).
PMID: 33925586
The p21 protein, encoded by , plays a vital role in senescence, and its transcriptional control by the tumour suppressor p53 is well-established. However, p21 can also be regulated in...
15.
Sikora E, Bielak-Zmijewska A, Dudkowska M, Krzystyniak A, Mosieniak G, Wesierska M, et al.
Front Aging Neurosci
. 2021 Mar;
13:646924.
PMID: 33732142
Aging of the brain can manifest itself as a memory and cognitive decline, which has been shown to frequently coincide with changes in the structural plasticity of dendritic spines. Decreased...
16.
Piszczatowska K, Przybylska D, Sikora E, Mosieniak G
Antioxidants (Basel)
. 2020 Dec;
9(12).
PMID: 33302580
NADPH oxidases (NOX) are commonly expressed ROS-producing enzymes that participate in the regulation of many signaling pathways, which influence cell metabolism, survival, and proliferation. Due to their high expression in...
17.
Jaworska K, Hering D, Mosieniak G, Bielak-Zmijewska A, Pilz M, Konwerski M, et al.
Toxins (Basel)
. 2019 Aug;
11(9).
PMID: 31454905
Trimethylamine-N-oxide (TMAO) has been suggested as a marker and mediator of cardiovascular diseases. However, data are contradictory, and the mechanisms are obscure. Strikingly, the role of the TMAO precursor trimethylamine...
18.
Jaworska K, Konop M, Hutsch T, Perlejewski K, Radkowski M, Grochowska M, et al.
J Gerontol A Biol Sci Med Sci
. 2019 Aug;
75(7):1276-1283.
PMID: 31411319
It has been suggested that trimethylamine oxide (TMAO), a liver oxygenation product of gut bacteria-produced trimethylamine (TMA), is a marker of cardiovascular risk. However, mechanisms of the increase and biological...
19.
Sikora E, Bielak-Zmijewska A, Mosieniak G
Ageing Res Rev
. 2019 Aug;
55:100941.
PMID: 31408714
Senotherapy is an antiageing strategy. It refers to selective killing of senescent cells by senolytic agents, strengthening the activity of immune cells that eliminate senescent cells or alleviating the secretory...
20.
Grabowska W, Mosieniak G, Achtabowska N, Czochara R, Litwinienko G, Bojko A, et al.
Biogerontology
. 2019 Aug;
20(6):783-798.
PMID: 31372798
Curcumin, a phytochemical present in the spice named turmeric, and one of the promising anti-aging factors, is itself able to induce cellular senescence. We have recently shown that cells building...